67977-00-8

Upstream product

• 93716-18-8 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (1R,2R)-2-bromo-1,2,3,4-tetrahydro-dibenzo[c,h]acridin-1-yl ester 
• 93716-18-8 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (1S,2S)-2-bromo-1,2,3,4-tetrahydro-dibenzo[c,h]acridin-1-yl ester 
• 93716-15-5 trans-2-bromo-1-hydroxy-1,2,3,4-tetrahydrodibenzacridine 
• 93716-15-5 (1S,2S)-2-bromo-1-hydroxy-1,2,3,4-tetrahydrodibenzacridine 
• 76186-80-6 1-hydroxy-1,2,3,4-tetrahydro-dibenzacridine 
• 76186-82-8 3,4-dihydro-dibenzacridine 
• 76186-77-1 1,2,3,4-tetrahydro-dibenzacridine 
• 2217-41-6 1-amino-5,6,7,8-tetrahydronaphthalene 
• 90-15-3 α-naphthol 
• 224-53-3 dibenz[c,h]acridine 

Downstream Products

• 93716-21-3 trans-5,6-dihydroxy-5,6-dihydrodibenzacridine 
• 93716-21-3 cis-5,6-dihydroxy-5,6-dihydrodibenzacridine 

Relevant academic research and scientific papers

Mono-, and Dibenzacridine Imines. Synthesis of 1a,11b-Dihydrobenzazirinoacridine, 4b,5a-Dihydrodibenzazirinoacridine and 1a,13b-Dihydrodibenzazirinoacridine

The syntheses of the K-imine derivatives of benzacridine, dibenzacridine and dibenzacridine are described.The parent hydrocarbons 1, 6 and 11 were oxidized with sodium hypochlorite under phase transfer conditions to the corresponding K-oxides 4, 9 and 14, which in turn were reacted with sodium azide.The resulting azido alcohols were then cyclized with tributylphosphine to the title compounds 5, 10 and 15.

Synthesis of Enantiomerically Pure Bay-Region 3,4-Diol 1,2-Epoxide Diastereomers and Other Derivatives of the Potent Carcinogen Dibenzacridine

The four enantiomerically pure bay-region 3,4-diol 1,2-epoxide diastereomers of dibenzacridine were synthesized from the corresponding pure trans-3,4-dihydroxy-3,4-dihydrodibenzacridine enantiomers.Racemic trans-3,4-dihydroxy-3,4-dihydrodibenzc