679795-37-0

Usage

Physical state

Colorless liquid

Odor

Fruity

Uses

Production of pharmaceuticals, agrochemicals, flavor and fragrance products

Potential

Building block in organic synthesis, precursor in the development of new chemical compounds with biological or pharmacological activity

Preferred form

Ethyl ester for stability and ease of handling in laboratory settings.

Upstream product

• 401-55-8 ethyl bromofluoroacetate 
• 104-55-2 3-phenyl-propenal 
• 565-53-7 ethyl dibromofluoroacetate 

Relevant academic research and scientific papers

Diethylzinc-mediated one-step stereoselective synthesis of α-fluoroacrylates from aldehydes and ketones. Two different pathways depending on the carbonyl partner

(Chemical Equation Presented) A efficient methodology allowing the one-pot stereoselective synthesis of R-fluoroacrylates, based on the addition of ethyl dibromofluoroacetate to a carbonyl derivative using diethylzinc as organometallic mediator, is descri

Microwave-assisted one-pot synthesis of α-fluoro-α,β- unsaturated esters under solvent-free conditions

A microwave-assisted approach for the synthesis of α-fluoro-α, β-unsaturated esters from ethyl bromofluoroacetate, aldehydes, and triphenylphosphine in the presence of Zn-Cu under solvent-free conditions was achieved. The reaction was accomplished within