679805-33-5

Usage

Molecular Structure

The compound 1H-Pyrazolo[3,4-d]pyrimidine, 1-(2-chloro-2-phenylethyl)-6-(methylthio)-4-(4-morpholinyl)contains a pyrazole ring structure and various functional groups such as chloro, phenylethyl, methylthio, and morpholinyl.

Chemical Class

It belongs to the class of pyrimidine derivatives.

Potential Applications

The compound has potential pharmaceutical and biochemical applications.

Suitability for Research

The compound is suitable for drug development and medicinal chemistry research due to its functional groups.

Exploration of Properties and Activities

The specific properties and potential biological activities of the compound are yet to be fully explored, making it a subject of interest in drug discovery and pharmaceutical research.

Upstream product

• 679805-47-1 ethyl 5-{[(benzoylamino)carbonothioyl]amino}-1-(2-hydroxy-2-phenylethyl)-1H-pyrazole-4-carboxylate 
• 679805-49-3 1-(2-hydroxy-2-phenylethyl)-6-(methylthio)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 
• 679805-48-2 1-(2-hydroxy-2-phenylethyl)-6-thioxo-1,5,6,7-tetrahydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 
• 383911-62-4 5-amino-1-(2-hydroxy-2-phenylethyl)-1H-pyrazole-4-carboxylic acid ethyl ester 
• 110-91-8 morpholine 
• 679805-51-7 4-chloro-1-(2-chloro-2-phenylethyl)-6-(methylthio)-4H-pyrazolo[3,4-d]pyrimidin-4-one 

Relevant academic research and scientific papers

Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation

We report here the synthesis of new pyrazolo[3,4-d]pyrimidine derivatives along with their biological properties as inhibitors of isolated Src and cell line proliferation (A431 and 8701-BC cells). Such compounds block the growth of cancer cells by interfe

Pyrazolo[3,4-d]pyrimidines Endowed with Antiproliferative Activity on Ductal Infiltrating Carcinoma Cells

Novel 1,4,6-trisubstituted pyrazolo[3,4-d]pyrimidines are reported with preliminary in vitro activity data indicating that several of them are potent inhibitors (better than the reference compound) of Src phosphorylation of the breast cancer cells 8701-BC

Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1H-pyrazolo[3,4-d] pyrimidines 4-amino substituted and their biological evaluation

A new series of 4-amino-6-methylthio-1H-pyrazolo[3,4-d]pyrimidines (2a-m) bearing the 2-chloro-2-phenylethyl chain at the N1 position, has been synthesized. The affinity of these compounds for A1 adenosine receptor (A1AR) was measure

New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation

New 4-aminopyrazolo[3,4-d]pyrimidines bearing various substituents at the position 1 and 6, were synthesized. The new compounds showed antiproliferative activity toward A431 cells, were found to be inhibitors of Src phosphorylation, and induced apoptotic

4-SUBSTITUTED DERIVATIVES OF PYRAZOLO[3,4-d]PYRIMIDINE AND PYRROLO[2,3-d]PYRIMIDINE AND USES THEREOF

4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine are described. Compounds are active as antitumoural agents.