679805-58-4Relevant academic research and scientific papers
New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation
Schenone,Bruno,Ranise,Bondavalli,Brullo,Fossa,Mosti,Menozzi,Carraro,Naldini,Bernini,Manetti,Botta
, p. 2511 - 2517 (2004)
New 4-aminopyrazolo[3,4-d]pyrimidines bearing various substituents at the position 1 and 6, were synthesized. The new compounds showed antiproliferative activity toward A431 cells, were found to be inhibitors of Src phosphorylation, and induced apoptotic
