67985-36-8Relevant academic research and scientific papers
Synthesis and activity of some quinolone derivatives against Plasmodium falciparum in vitro
Dominguez,Basante,Charris,Riggione
, p. 407 - 412 (2007/10/03)
Quinolones 7a-i and 8a-i were synthesized and tested in vitro as antimalarial against Plasmodium falciparum in chloroquine resistant strain. The above compounds were inactive at concentrations of 1.0 x 10-4 M except the quinolone 3-amino-9-(2,4-dichlorophenyl)-1H-pyrazolo[3,4-b]-4-quinolone 7h which showed IC50 of 5.06 μM given the most interesting results.
