68012-05-5

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 68-12-2 N,N-dimethyl-formamide 
• 77287-34-4 formamide 
• 149-73-5 trimethyl orthoformate 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 142781-81-5 2-acetyl-3-o-anisidino-acrylic acid ethyl ester 
• 292642-61-6 [Cr₂(N,N'-bis(o-anisyl)formamidinate)4] 
• 850220-13-2 N,N'-di(2-methoxyphenyl)formamidine*copper(II) chloride 
• 1192371-32-6 1,3-di(2-anisidyl)-4,5,6,7-tetrahydro-3H-[1,3]diazepinium iodide 
• 1192371-33-7 1,3-di(2-anisidyl)-3,4,5,6-tetrahydro-3H-[1,3]pyrimidinium bromide 
• 1118916-94-1 1,3-bis(2-methoxyphenyl)-4,5,6,7-tetrahydro-3H-benzoimidazol-1-ium bromide 
• 850220-19-8 [N,N'-di(2-methoxyphenyl)formamidine]2PdCl₂ 
• 464191-10-4 trans-[Mo₂(trifluoroacetate)2(N,N'-di(2-methoxyphenyl)formamidinate)2] 
• 464191-09-1 trans-[Mo₂(acetate)2(N,N'-di(2-methoxyphenyl)formamidinate)2] 
• 464191-08-0 Mo₂(O₂CCH₃)3(CH₃OC₆H₄N)2CH 

Relevant academic research and scientific papers

Synthesis and structure of group 4 symmetric amidinate complexes and their reactivity in the polymerization of α-olefins

The steric properties of various nitrogen substituents on amidines were tuned in order to obtain group 4 mono- and bis(amidinate) dimethylamido or chloride complexes. The amidinate dimethylamido and chloride complexes were prepared, and their solid-state

Deep eutectic solvent promoted highly efficient synthesis of N, N'-diarylamidines and formamides

A deep eutectic solvent was used as a dual catalyst and reaction medium for the efficient N-formylation of aromatic amines without hazardous organic solvent and catalyst. Treatment of aromatic amines with trimethyl orthoformate and formic acid in deep eutectic solvent at 70 °C gives the corresponding N-formyl derivatives in good to excellent yields. This simple ammonium deep eutectic solvent, easily synthesized from choline chloride and SnCl2, with 100% atom economy and making it applicable to industry and laboratory. Furthermore, heating the trimethyl orthoformate and aromatic primary amines in the deep eutectic solvent results in formation of the corresponding N,N'-diarylamidines in high yields.

Evaluation of electrophilic heteroaromatic substitution: Synthesis of heteroaromatic-fused pyrimidine derivatives via sequential three-component heterocyclization

A new sequential three-component heterocyclization was developed by reacting aromatic and heterocyclic substrates, including aminobenzenes, 1-aminonaphthalene, 2-aminopyrazines, 5-aminopyrazoles, 3-aminopyridine, 5-aminopyrimidine, 5-aminoquinoline, and 8

Amine exchange in formamidines: An experimental and theoretical study

N-H-containing formamidines combine a reasonably strong association to carboxylic acids to form complexes of well-defined geometries with a simultaneous proton-induced electrophilicity enhancement that allows for the exchange of their amine portion. The N

Expanded ring and functionalised expanded ring N-heterocyclic carbenes as ligands in catalysis

The synthesis of new functionalised 6- and 7-membered NHC (N-heterocyclic carbene) precursors bearing anisidyl or pyridine N-substituents, both symmetrically and non-symmetrically substituted is reported. Their corresponding rhodium(i) and iridium(i) complexes, M(COD)(NHC)Cl, were also prepared and characterised. The unusual Rh(iii)/Rh(i) salt, [Rh(η2-NHC-py) 2Cl2][Rh(COD)Cl2], was obtained with one of the pyridyl-functionalised NHC ligands. Single-crystal X-ray analyses have been obtained for the majority of the complexes and NHC salts. The activity of these complexes was tested in the hydrogenation of a range of substrates with molecular hydrogen, including 1-cyclooctadiene and 2-methyl styrene, where they show enhanced activity and stability in comparison to non-functionalised NHC analogues, operating under exceptionally mild conditions (ambient temperature and atmospheric pressure).

A modular synthesis of highly substituted imidazolium salts

A versatile and modular one-pot method for the preparation of differently substituted symmetrical and unsymmetrical imidazolium salts is reported, and 19 examples are given. In the key step, readily available formamidines and α-halo ketones are coupled to give imidazolinium salts 3, followed by imidazolium salt formation by acylation-induced elimination. For many substitution patterns of the imidazolium salt products, this efficient strategy compares favorably with well-known processes in terms of yield, ease of synthesis, and robustness.