68036-18-0Relevant academic research and scientific papers
The Glc2Man2-fragment of the N-glycan precursor - A novel ligand for the glycan-binding protein malectin?
Mueller, Lisa N.,Muhle-Goll, Claudia,Biskup, Moritz B.
supporting information; experimental part, p. 3294 - 3299 (2010/08/21)
The Glcα(1→3)Glcα(1→3)Manα(1→2)Man tetrasaccharide (Glc2Man2-fragment), a substructure of the natural N-glycan precursor, was synthesized. The interaction of this fragment with the protein malectin, a carbohydrate binding protein localized in the endoplasmatic reticulum, was investigated by 1H15N HSQC experiments and isothermal calorimetry. The chemical shift perturbations of nuclei in the protein's backbone caused by the binding of the Glc 2Man2-fragment to malectin suggest a binding mode like the known ligand nigerose. The Royal Society of Chemistry 2010.
A Chemoenzymatic route to conjugatable β(1→3)-Glucan Oligosaccharides
Montel, Emilie,Hrmova, Maria,Fincher, Geoffrey B.,Driguez, Hugues,Cottaz, Sylvain
experimental part, p. 575 - 584 (2010/01/16)
3II-O-Allyl-α laminaribiosyl fluoride was prepared as a key synthon for the enzymatic synthesis of β(1→3)-glucan oligosaccharides, catalyzed by a mutated β(1→3)-glucanase (E231G) from barley (Hordeum vulgare L.). A strategy was developed for en
The Synthesis of Active-Site Directed Inhibitors of Some β-Glucan Hydrolases
Rodriguez, Evelyn B.,Stick, Robert V.
, p. 665 - 679 (2007/10/02)
The 2,3-epoxypropyl, 3,4-epoxybutyl and 4,5-epoxypentyl β-glycosides of D-glucose, cellobiose and laminaribiose have been prepared.As well, the 4,5-epoxypentyl β-glycosides of cellotriose, laminaritriose and two other trisaccharides have been synthesized. 3,4-Epoxybutyl β-cellobioside has also been prepared with a 14C-label in the cellobiose residue.
SYNTHESIS OF A BRANCHED D-GLUCOTETRAOSE, THE REPEATING UNIT OF THE EXTRACELLULAR POLYSACCHARIDES OF Grifola umbellate, Sclerotinia libertiana, Porodisculus pendulus, AND Schizophyllum commune FRIES
Ogawa, Tomoya,Kaburagi, Toshiaki
, p. 53 - 64 (2007/10/02)
The synthesis of D-glucotetraose, 3-O--6-O-β-D-glucopyranosyl-α (and β)-D-glucopyranose, the repeating unit of the extracellular polysaccharides of Grifora umbellata, Sclerotinia libertiana, Porodisculus pendulus, and Schizophyllum commune Fries, is described.
