68063-31-0

Upstream product

• 90787-08-9 (4R,4aS)-2,4a-Dimethyl-5-oxo-4-phenyl-4a,5-dihydro-4H-indeno[1,2-b]pyridine-3-carboxylic acid ethyl ester 
• 5381-33-9 2-benzylidene-indan-1,3-dione 
• 1522-41-4 ethyl-2-fluoroacetoacetate 
• 26576-79-4 2-Methyl-3-ethoxycarbonyl-4-phenyl-5-oxo-4,5-dihydro-1H-indeno<1,2-b>pyridine 
• 626-34-6 ethyl aminocrotonate 

Relevant academic research and scientific papers

One-Pot Reactions for Modular Synthesis of Polysubstituted and Fused Pyridines

A 2-fluoro-1,3-dicarbonyl-initiated one-pot Michael addition/[5 + 1] annulation/dehydrofluorinative aromatization reaction sequence is introduced for regioselective synthesis of di-, tri-, tetra-, and pentasubstituted pyridines as well as fused pyridines. This simple and modular synthesis is performed using readily available starting materials and under transition-metal catalyst-free conditions.

Synthesis and alkylation of 4-aryl-5-oxo-1h-2,3,4,5-tetrahydroindeno[1,2-b] pyridines

Reduction of 5-oxo-4-phenyl-1H-4,5-dihydroindeno[1,2-b]pyridines with triethylsilane in trifluoro-acetic acid gave the corresponding 1,2,3,4-tetrahydroindeno[1,2-b]pyridines predominatly with the trans-configured substituents at atoms C(2), C(3), and C(4)

Synthesis and isomerization of 1H-4,4a,5,9b-tetrahydroindeno-[1,2-b]pyridines

Synthesis of 1H-4,4a,5,9b-tetrahydroindeno[1,2-b]pyridines has been accomplished by catalytic hydrogenation of 4H-4a,5-dihydroindenopyridines. The isomerization of 1H-4,4a,5,9b-tetrahydroindenopyridines containing an acyl function at C-3 leads to 3H-4,4a,