68094-92-8

Upstream product

• 16690-93-0 sodium β-alaninate 
• 79-50-5 pantolactone 
• 107-95-9 3-amino propanoic acid 
• 1377411-51-2 ethyl (S)-3-(benzyloxy)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethylpropanoate 
• 1377411-48-7 ethyl (S)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-hydroxy-2,2-dimethylpropanoate 
• 1377411-57-8 methyl 3-[(S)-4-acetoxy-2-(benzyloxy)-3,3-dimethylbutanoylamino]propanoate 
• 1377411-56-7 (2S)-4-acetoxy-2-(benzyloxy)-3,3-dimethylbutanoic acid 
• 1377411-55-6 (S)-3-(benzyloxy)-2,2-dimethyl-4-oxobutyl acetate 
• 1377411-54-5 (3S,4R)-3-(benzyloxy)-4,5-dihydroxy-2,2-dimethylpentyl acetate 
• 1377411-53-4 (S)-3-(benzyloxy)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethylpropyl acetate 
• 895532-73-7 (S)-3-(benzyloxy)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethylpropan-1-ol 
• 137-08-6 calcium-N-(2,4-dihydroxy-3,3-dimethylbutyryl)-β-alaninate 
• 597-31-9 2,2-dimethyl-3-hydroxypropionaldehyde 
• 7732-18-5 water 

Relevant academic research and scientific papers

AN INVESTIGATION OF THE STABILITY OF THE PHOSPHATE ESTER BOND IN D-PANTOTHENIC ACID 4'-PHOSPHATE

The hydrolysis of the phosphate ester bond in D-pantothenic acid 4'-phosphate in strongly acid (9 and 6 N HCL), weakly acid, weakly alkaline, and strongly alkaline (5 N KOH) aqueous media has been studied.In strongly acid and strongly alkaline media the phosphate ester bond of (I) breaks down completely in 3 and 2.5 h, respectively.The rate of hydrolysis at pH values between 1.3 and 11 remains constantly low but almost doubles in the presence of lanthanum salts at pH 8-9 and in the presence of lithium salts at pH 4 and a molar ratio of (I):Me+ = 1:1.

Enantiodivergent syntheses of pantolactone and pantothenic acid from d -mannitol

Efficient synthetic routes to both the enantiomers of pantolactone and pantothenic acid have been developed starting from d-mannitol-based d-glyceraldehyde acetonide through its conversion into a protected pantoic acid intermediate followed by either cyclization or amide bond formation with a -amino ester, and subsequent appropriate deprotection. Georg Thieme Verlag Stuttgart . New York.

STIMULANT OF HAIR GROWTH BASED ON A PANTOTHENIC ACID DERIVATIVE

Stimulant of hair growth based on a pantothenic acid derivative The invention relates to cosmetic industry and relates to application of new derivatives of pantothenic acid, namely, ammonium salts with peptides of the following formula (I) where X i s GIy, Ala , Leu , lie , VaI , Pro , Tyr , Phe , Trp , D- IIe , γ-aminobutyric acid ; Y is GIu , Z is OH, NH2, mono- or disubstituted amide (C1-C3) , alkyl ester (C1 - C3) , as well as conjugates of pantothenic acid with peptides of the following formula (II) where X is Gly, Ala , Leu, lie , VaI , Pro , Tyr , Phe , Trp ,D-Ile , γ-aminobutyric acid; Y i s Glu, Z is OH, NH2, mono- or disubstituted amide (C1-C3) , alkyl ester (C1- C3) as a hair growth stimulant, and also a method of preparation of these derivatives.