Chemistry of Natural Compounds p. 220 - 223 (1987)
Update date:2022-08-02
Topics:
Moiseenok, A. G.
Slyshenkov, V. S.
Dedovich, T. V.
The hydrolysis of the phosphate ester bond in D-pantothenic acid 4'-phosphate in strongly acid (9 and 6 N HCL), weakly acid, weakly alkaline, and strongly alkaline (5 N KOH) aqueous media has been studied.In strongly acid and strongly alkaline media the phosphate ester bond of (I) breaks down completely in 3 and 2.5 h, respectively.The rate of hydrolysis at pH values between 1.3 and 11 remains constantly low but almost doubles in the presence of lanthanum salts at pH 8-9 and in the presence of lithium salts at pH 4 and a molar ratio of (I):Me+ = 1:1.
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Doi:10.1021/ja01122a063
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(1987)
