681124-12-9Relevant academic research and scientific papers
Synthesis and DNA damaging ability of enediyne-polyamine conjugates
Suzuki, Ichiro,Shigenaga, Akira,Nemoto, Hisao,Shibuya, Masayuki
, p. 1955 - 1959 (2007/10/03)
Polyamine-enediyne conjugates were synthesized and exhibited potent DNA damaging ability under physiological conditions. The extent of their activity was shown to depend upon the polyamine length that regulates the DNA binding affinity of the conjugates,
