681129-08-8Relevant articles and documents
Appending a tris-imidazole ligand with a Tyr244 mimic on the distal face of bromoacetamidoporphyrin
Collman, James P.,Decreau, Richard A.,Costanzo, Simona
, p. 1033 - 1036 (2007/10/03)
(Equation presented) Bromoacetamidoporphyrin is a convenient synthon for the attachment of distal superstructures at room temperature in good yields. New models are presented that contain a tris-imidazole distal ligand set bound to the porphyrin in either a binary or trinary fashion. More importantly, one distal imidazole is cross-linked to a phenol mimicking Tyr244, making this model the closest structural analogue yet reported of the metal free cytochrome c oxidase (CcO) active site.