681260-24-2Relevant articles and documents
Synthesis and antimicrobial evaluation of (Z)-5-((3-phenyl-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one derivatives
Wei, Zhi-Yu,Liu, Jia-Chun,Zhang, Wen,Li, Ya-Ru,Li, Chao,Zheng, Chang-Ji,Piao, Hu-Ri
, p. 751 - 759 (2016/11/29)
Background: An alarming increment in pathogenic resistance to existing anti-microbial agents is a serious problem and the treatment of these bacterial infections is becoming increasingly challenging. Therefore, there is an urgent need to develop novel ant
New INH-pyrazole analogs: Design, synthesis and evaluation of antitubercular and antibacterial activity
Nayak, Nagabhushana,Ramprasad, Jurupula,Dalimba, Udayakumar
, p. 5540 - 5545 (2015/11/17)
With the aim of developing promising antitubercular and antibacterial leads, we have designed and synthesized a new series of isonicotinohydrazide based pyrazole derivatives (5a-r). All new derivatives (4a-b and 5a-r) were screened for in vitro antimycoba