6814-99-9Relevant articles and documents
Process for preparing 2-aminothiazole-5-carboxamides useful as kinase inhibitors
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Page/Page column 13, (2008/06/13)
The invention is directed to processes for preparing 2-aminothiazole-5-carboxamides of formula I [image] wherein R1, R2, R3, R4 and R5 are as defined as set forth in the specification herein.
A convenient and efficient method for the synthesis of mono- and N,N-disubstituted thioureas
Kodomari, Mitsuo,Suzuki, Masato,Tanigawa, Keiko,Aoyama, Tadashi
, p. 5841 - 5843 (2007/10/03)
A convenient method for the synthesis of mono- and N,N-disubstituted thioureas by the debenzoylation of N-substituted- and N,N-disubstituted- N′-benzoylthioureas with hydrazine hydrate under solvent-free conditions has been developed. N-Substituted-N′-benzoylthioureas and hydrazine hydrate were mixed, and stirred at room temperature without a solvent to give the corresponding N-substituted thioureas in high yields.