6814-99-9

Basic information

• Product Name: SEC-BUTYL-THIOUREA
• Synonyms: 1-sec-Butylthiourea; sec-Butyl-thiourea; thiourea, N-(1-methylpropyl)-
• CAS NO: 6814-99-9
• Molecular Formula: C₅H₁₂N₂S
• Molecular Weight: 132.23
• Mol File: 6814-99-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 137 °C
• Boiling Point: 194.6°C at 760 mmHg
• Flash Point: 71.5°C
• Appearance: /
• Density: 1.025g/cm³
• Vapor Pressure: 0.437mmHg at 25°C
• Refractive Index: 1.526
• PKA: 14.79±0.29(Predicted)
• CAS DataBase Reference: SEC-BUTYL-THIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: SEC-BUTYL-THIOUREA(6814-99-9)
• EPA Substance Registry System: SEC-BUTYL-THIOUREA(6814-99-9)

Safety Data

• Hazardous Substances Data: 6814-99-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H12N2S/c1-3-4(2)7-5(6)8/h4H,3H2,1-2H3,(H3,6,7,8)

Upstream product

• 116724-11-9 sec-butyl isothiocyanate 
• 89487-47-8 (1-methyl-allyl)-thiourea 
• 7732-18-5 water 
• 513-49-5 (S)-2-aminobutane 
• 532-55-8 Benzoyl isothiocyanate 
• 623-45-0 (S)-Butyl-⁽²⁾-isothiocyanat 
• 2253-92-1 but-2-enylsulfanyl cyanate 
• 2253-71-6 1-methyl-allyl isothiocyanate 
• 25343-21-9 1-Benzoyl-3-sec-butyl-thiourea 
• 14294-20-3 N-(sec-Butyl)-N'-(t-pentyl)-thioharnstoff 
• 14327-00-5 N-(sec-butyl)-N'-(tert-butyl)-thiourea 

Downstream Products

• 96112-87-7 17α-Hydroxy-17β-(2-sec-butylamino-thiazolyl-4-yl)-androst-4-en-3-one 

Relevant articles and documents

PROCESS FOR PREPARING 2-AMINOTHIAZOLE-5-AROMATIC CARBOXAMIDES AS KINASE INHIBITORS

The invention relates to processes for preparing compounds having the formula (I) and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.

THIAZOLE DERIVATIVES AND USE THEREOF

The present invention is related to thiazole derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.