681440-03-9

Basic information

• Product Name: Benzenesulfonamide, 2-methoxy-N-phenyl-N-(phenylmethyl)-
• CAS NO: 681440-03-9
• Molecular Formula: C20H19NO3S
• Molecular Weight: 353.442
• Mol File: 681440-03-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 2-methoxy-N-phenyl-N-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 2-methoxy-N-phenyl-N-(phenylmethyl)-(681440-03-9)
• EPA Substance Registry System: Benzenesulfonamide, 2-methoxy-N-phenyl-N-(phenylmethyl)-(681440-03-9)

Safety Data

• Hazardous Substances Data: 681440-03-9(Hazardous Substances Data)

Upstream product

• 100-66-3 methoxybenzene 
• 62-53-3 aniline 
• 10130-87-7 o-Methoxybenzenesulfonyl chloride 
• 160878-46-6 2-methoxy-N-phenylbenzenesulfonamide 

Downstream Products

• 758640-21-0 N-Benzylaniline 

Relevant articles and documents

ortho-anisylsulfonyl as a protecting group for secondary amines: Mild Ni0-catalyzed hydrodesulfonylation

A potentially good alternative to the tosyl group (Ts) as a protecting group for amines is N-ortho-anisylsulfonyl (Ans), which is readily cleaved under mild, Ni0-catalyzed reductive conditions (see scheme, acac = acetylacetonate). N-Anisylation of primary amines followed by alkylation and deprotection provides a route to a range of secondary amines.