681853-92-9

Usage

Uses

Used in Organic Synthesis:
(1R,4S,5S)-(+)-4,5-isopropylidenedioxy-1-(tert-butyldiphenylsilyloxymethyl)-2-cyclopenten-1-ol is used as a chiral building block for the synthesis of complex organic compounds. Its unique structure and functional groups allow for versatile reactions and the creation of a wide range of molecules with potential applications in various industries.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (1R,4S,5S)-(+)-4,5-isopropylidenedioxy-1-(tert-butyldiphenylsilyloxymethyl)-2-cyclopenten-1-ol is utilized as a key intermediate in the development of pharmaceutical compounds. Its specific stereochemistry and functional groups can be leveraged to design and synthesize novel drugs with improved efficacy and selectivity.
Used in Pharmaceutical Industry:
(1R,4S,5S)-(+)-4,5-isopropylidenedioxy-1-(tert-butyldiphenylsilyloxymethyl)-2-cyclopenten-1-ol is used as a precursor in the synthesis of pharmaceutical compounds. Its unique structure and functional groups make it a valuable asset in the development of new drugs, potentially leading to breakthroughs in the treatment of various diseases and conditions.
Further study and characterization of (1R,4S,5S)-(+)-4,5-isopropylidenedioxy-1-(tert-butyldiphenylsilyloxymethyl)-2-cyclopenten-1-ol's properties and reactivity are necessary to fully understand and exploit its potential for various chemical and pharmaceutical applications.

Upstream product

• 952418-10-9 (1R)-(+)-1-[(4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]-1-[(tert-butyldiphenylsilyloxy)methyl]-2-propen-1-ol 
• 67814-68-0 2,3-O-isopropylidene-D-ribofuranose 
• 10257-32-6 D-ribose 
• 532-20-7 D-Ribose 
• 96690-02-7 5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose 
• 902799-70-6 C₂₇H₃₆SiO₄ 
• 50-69-1 D-ribose 
• 681853-95-2 (-)-1-[(4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]-2-(tert-butyldiphenylsilyloxy)ethan-1-one 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 72877-50-0 neplanocin A 
• 303963-93-1 (3aS,4S,6aR)-6-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyl-3a,6a-dihydro-4H-cyclopenta[d][1,3]dioxol-4-ol 
• 915694-38-1 (3aR,3bR,4aS,5S,5aS)-3b-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethylhexahydrocyclopropa[3,4]cyclopenta[1,2-d][1,3]dioxol-5-ol 
• 303963-92-0 (3aR,6aR)-6-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyl-3a,6a-dihydro-4H-cyclopenta[d][1,3]dioxol-4-one 

Relevant academic research and scientific papers

COMPOUNDS AND METHODS FOR TREATING ADDICTION AND RELATED DISORDERS

The present invention relates to compounds and methods of use thereof for treatment of certain disorders and conditions, for example an addiction or compulsive disorder.

Compounds and methods for treating neurological and cardiovascular conditions

The present invention relates to compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries.

Total syntheses of a conformationally locked North-type methanocarba puromycin analogue and a dinucleotide derivative

An original synthetic approach for the first synthesis of an enantiopure methanocarba puromycin (3'-α-aminoacylamino-3'-deoxyadenosine) analogue and its cytidine dinucleotide derivative is described. Each compound is conformationally locked in a North-typ

Synthesis of (-)-neplanocin A with the highest overall yield via an efficient Mitsunobu coupling

Neplanocin A was synthesized in very high isolated yield and purity, in 10 steps from d-ribose via an efficient Mitsunobu coupling using N6-bis-Boc-protected adenine. In fact, this synthesis is a short pathway to enantiopure neplanocin A giving

Stereoselective synthesis of 3-hydroxymethyl-D-cyclopentenone, the versatile intermediate for the synthesis of carbocyclic nucleosides

The preparative and stereoselective synthesis (45-50% overall yields, >50 g scale) of the key carbasugars 7a-d was achieved from D-ribose via stereoselective Grignard reaction and oxidative rearrangement as key reactions. Copyright Taylor & Francis, Inc.

Preparative and Stereoselective Synthesis of the Versatile Intermediate for Carbocyclic Nucleosides: Effects of the Bulky Protecting Groups to Enforce Facial Selectivity

The preparative and stereoselective synthesis (45-50% overall yields) of the target compound 17 has been accomplished from D-ribose. The bulky protecting groups such as TBDPS and Trityl enforced the facial selectivity during Grignard reaction to give the