68276-72-2

Upstream product

• 16212-05-8 (allylsulfonyl)benzene 
• 3112-85-4 methylphenylsulfonate 
• 75-07-0 acetaldehyde 
• 937-56-4 1-phenylsulfanyl-propan-2-ol 
• 64-19-7 acetic acid 
• 108-98-5 thiophenol 
• 5042-53-5 1-(phenylsulfanyl)acetone 
• 28975-80-6 Phenyl-propenyl-sulfon 
• 764583-11-1 2-[(1E)-prop-1-en-1-ylsulfonyl]pyridine 
• 930-69-8 sodium thiophenolate 
• 203641-90-1 Acetic acid 2-benzenesulfonyl-1-methyl-ethyl ester 
• 873-55-2 sodium benzenesulfonate 
• 75-56-9 methyloxirane 
• 5000-44-2 1-phenylsulfonyl-2-propanone 

Downstream Products

• 112370-35-1 (2R,3R,4R)-3-Benzenesulfonyl-pentadecane-2,4-diol 
• 112370-35-1 (2R,3R,4S)-3-Benzenesulfonyl-pentadecane-2,4-diol 
• 66536-75-2 (S)-(+)-1-(phenylsulfonyl)propan-2-ol 
• 132059-19-9 Butyric acid (S)-2-benzenesulfonyl-1-methyl-ethyl ester 
• 132059-19-9 Butyric acid (R)-2-benzenesulfonyl-1-methyl-ethyl ester 
• 102838-84-6 (R)-1-(phenylsulphonyl)propan-2-ol 
• 28691-72-7 (E)-1-propenyl phenyl sulfone 
• 862249-93-2 acetic acid (R)-2-phenylsulfonyl-1-methylethyl ester 
• 64329-88-0 (E)-((2-phenylprop-1-en-1-yl)sulfonyl)benzene 
• 10277-54-0 (2S,3R)-3-Benzenesulfonyl-butan-2-ol 
• 10277-54-0 threo-(R^*,R^*)-phenyl 3-hydroxy-2-butyl sulfone 
• 106-48-9 4-chloro-phenol 

Relevant academic research and scientific papers

Switching of the Direction of Enzyme-Mediated Oxidation and Reduction of Sulfur-Substituted 2-Propanols and 2-Propanones

Incubation of 1-(phenylsulfenyl)-2-propanone with Corynebacterium equi IFO 3730 grown on hexadecane at pH 6.5 afforded the corresponding 1-substituted S propanols. 1-(Phenylsulfinyl)-2-propanone was also reduced by the microorganism, the product being aff

Selective hydrogen peroxide oxidation of sulfides to sulfones with carboxylated multi-walled carbon nano tubes (MWCNTs-COOH) as heterogeneous and recyclable nanocatalysts under organic solvent-free conditions

This study deals with oxidation of sulfides to sulfones by using a heterogeneous and recyclable nanocatalyst. Alkyl and aryl sulfides were directly oxidized to the corresponding sulfones in excellent yields with 30% H2O2 under organic solvent-free conditions, in the presence of carboxylated multi-walled carbon nano tubes (MWCNTs-COOH) as the efficient and heterogeneous nanocatalyst. The oxidation of alkyl and aryl sulfides proceeded at room temperature, and the corresponding sulfones were selectively obtained. The catalyst is recyclable for at least 8 cycles, and the only byproduct is water.

Catalytic asymmetric conjugate boration of α,β-unsaturated sulfones

The α,β-unsaturated sulfones are suitable activated olefins in catalytic asymmetric conjugate β-boration. These substrates undergo smooth conjugate addition of bis(pinacolato)diboron [B2(pin)2] catalyzed by nonracemic CuI-diphosphine complexes to provide, upon subsequent oxidation, β-hydroxy sulfones in good yields and high enantiocontrol.

The active role of NHC ligands in platinum-mediated tandem hydroboration-cross coupling reactions

Stable N-heterocyclic platinum-carbene complexes are the first example of platinum-mediated regioselective H-B addition to vinylarenes and alkynes, allowing consecutive cross coupling reactions with the same catalytic system. The Royal Society of Chemistry.

Enantioselective synthesis of chiral sulfones by Rh-catalyzed asymmetric addition of boronic acids to α,β-unsaturated 2-pyridyl sulfones

(Chemical Equation Presented) A general and efficient method for the rhodium-catalyzed enantioselective catalytic conjugate addition of organoboronic acids to α,β-unsaturated sulfones is described. The success of the process relies on the use of α,β-unsat

Heterofunctional control of regio- and enantioselectivity in rhodium-catalysed hydroboration of allylic systems

Aryl allylic sulfones were reacted with catecholborane (HBcat) in the presence of neutral and cationic Rh complexes modified with bidentate chiral ligands, to produce the branched heteroorganoboronate ester, as the main isomer with moderate enantioselecti

Lipase-promoted dynamic kinetic resolution of racemic β-hydroxyalkyl sulfones

A series of racemic aryl β-hydroxyalkyl sulfones have been successfully transformed into the corresponding optically active O-acetyl derivatives in high yields (up to 80%) with enantiomeric excesses more than 99% using a dynamic kinetic resolution procedure, in which a lipase-promoted kinetic resolution is combined with a concomitant ruthenium-catalysed racemization of the substrates.

Palladium-catalyzed cascade reaction of α,β-unsaturated sulfones with aryl iodides

Unlike traditionally used acyclic 1,2-disubstituted alkenes, the reaction of α,β-unsaturated phenyl sulfones with aryl iodides under Heck reaction conditions (Pd(OAc)2 as catalyst, Ag2-CO3 as base in DMF at 120°C) takes place mainly by a cascade process, involving one unit of the alkene and three units of the aryl iodide, to afford a substituted 9-phenylsulfonyl-9,10-dihydrophenanthrene, The dominant formation of this 3:1 coupling product, instead of the Heck trisubstituted olefin, shows that aromatic C-H activation processes can compete with the usually fast syn β-hydrogen elimination step in the Heck arylation of an acyclic olefin. The structural scope of this palladium-catalyzed cascade arylation of α,β-unsaturated sulfones has proved to be wide with regard to substitution at the β-position (alkyl, aryl, or alkenyl substitution), substitution at the sulfone unit (alkyl or phenyl sulfones), and configuration at the C=C bond (trans or cis). Moreover, although less favored than in the case of the arylation of α,β-unsaturated sulfones, similarly substituted 9,10-dihydrophenanthrenes have also been obtained in the case of α,β-unsaturated phosphine oxides and α,β-unsaturated phosphonate esters. A Pd0-pdII-pdIV mechanistic pathway involving the successive formation of highly electrophilic σ-alkylpalladium intermediates and palladacycles is proposed for this multi-component arylation.

Oxidation of sulfides to sulfoxides and sulfones with 30% hydrogen peroxide under organic solvent- and halogen-free conditions

Aromatic and aliphatic sulfides are oxidized to sulfoxides or sulfones in high yield with 30% hydrogen peroxide under organic solvent- and halogen-free conditions. Dialkyl and alkyl aryl sulfides are cleanly oxidized to sulfoxides using aqueous hydrogen peroxide without catalysts. The best catalyst for the sulfone synthesis consists of sodium tungstate, phenylphosphonic acid, and methyltrioctylammonium hydrogensulfate. Co-existing primary or secondary alcohol or olefinic moieties are unaffected under such conditions.

Facile synthesis of vinyl sulfones from β-bromo alcohols

Vinyl sulfones are synthesized in good yields by dehydration of β- hydroxy sulfones derived from β-bromo alcohols.