68276-73-3Relevant academic research and scientific papers
Synthesizing method of 3-sulfonyl alcohol compounds
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Paragraph 0013, (2017/04/03)
The invention discloses a synthesizing method of 3-sulfonyl alcohol compound. The method includes: using substituted sulfohydrazide and propenol compounds as the raw materials to perform reaction in water so as to obtain the 3-sulfonyl alcohol compounds. The method has the advantages that the method uses the substituted sulfohydrazide and the propenol compounds as the raw materials to perform the heating reaction in an aqueous solution without catalysts to directly obtain the 3-sulfonyl alcohol compounds, and the 3-sulfonyl alcohol compounds with the purity being above 80% can be obtained through simple separation after the reaction; the method is few in steps, simple to operate and green, and a new method for synthesizing medical and chemical alcohol compounds is provided for the chemical synthesizing field.
Catalytic asymmetric hydroboration of heterofunctional allylic substrates: an efficient heterogenized version
Lillo, Vanesa,Fernandez, Elena,Segarra, Anna M.
, p. 911 - 914 (2008/02/03)
The hydroboration of heterofunctional allylic systems with catecholborane (HBcat) using neutral and cationic rhodium complexes modified with P-P and P-N bidentate chiral ligands has been described in order to produce the secondary heteroorganoboronate ester as a major product with moderate enantioselectivity. The immobilization of cationic chiral rhodium complexes onto clays has beneficial effects on the recyclability and reuse of the catalytic system in particular for the hydroboration of allyl aryl sulfones.
The remarkable effect of methanol on sulfide photooxidations. Evidence for its dual reactivity
Clennan, Edward L.,Yang, Kang
, p. 1697 - 1700 (2007/10/02)
The addition of small amounts of methanol to photooxidation mixtures of sulfides dramatically enhances sulfone in preference to sulfoxide formation. High concentrations of methanol on the other hand have the opposite effect of promoting sulfoxide in prefe
Sulfone Directed Rhodium Catalysed Hydroboration: Regiochemistry in Acyclic System
Hou, Xue-Long,Hong, Dao-Guang,Rong, Guo-Bin,Guo, Yang-Long,Dai, Li-Xin
, p. 8513 - 8516 (2007/10/02)
Rhodium catalysed hydroboration of allyl sulfones gave rise to Markownikoff product with high regioselectivity.
"Syn-Effect" in the Conversion of (E)-Vinylic Sulfones to the Corresponding Allylic Sulfones
Hirata, Takaki,Sasada, Yoshihiro,Ohtani, Takashi,Asada, Takahiro,Kinoshita, Hideki,et al.
, p. 75 - 96 (2007/10/02)
It was found that (E)-vinylic sulfones preferentially afford (Z)-allylic sulfones as kinetically-controlled products by treatment with a base under mild conditions, while (Z)-vinylic sulfones give (E)-allylic sulfones.Such stereochemical relationship was
Remote Participation during Photooxidation at Sulfur. Eidence for Sulfurane Intermediates
Clennan, E. L.,Yang, Kang
, p. 4477 - 4487 (2007/10/02)
The photooxidations of geminally substituted γ-hydroxy sulfides results in formation of unusual oxidative elimination products.Detailed spectral data and the independent synthesis of a close analogue provide compelling evidence for the structures of these
ENANTIOSELECTIVE TOTAL SYNTHESIS OF (+)-NITRAMINE
Tanner, David,He, Hua Ming
, p. 4309 - 4316 (2007/10/02)
A short enantioselective synthesis of the spirocyclic alkaloid (+)-Nitramine (1) is reported, the azaspiro ring system being formed via intramolecular ring-opening of the chiral epoxy sulfone 7.
MODERN FRIEDEL-CRAFTS CHEMISTRY. XIV. ON THE CYCLIZATION OF SELECTED ARYL HYDROXYALKYL SULFIDES
El-Khawaga, A. M.,El-Zohry, M. F.,Ismail, M. T.,Abdel-Wahab, A. A.,Khalaf, A. A.
, p. 265 - 270 (2007/10/02)
The feasibility of cycloalkylation reactions in the presence of Friedel-Crafts catalysts was demonstrated in a nimber of aryl hydroxyalkyl sulfides (1-5), and benzyl hydroxyalkyl sulfides (6-7).Treatment of compounds (1-7) with Friedel-Crafts catalysts gave diaryl disulfides, diaryl sulfides, arene thiols, chlorohydrins, aryl chloroalkyl sulfides, aryl alkenyl sulfides and cyclization products.It is noteworthy to mention that cyclization products were isolated only in cases where the hydroxyl group is linked to a tertiary carbon atom as in compounds 3 and 7.A suitable reaction pathway is suggested to rationalize the formation of the various reaction products.
