125993-11-5

Upstream product

• 125943-20-6 Trifluoro-methanesulfonic acid (1R,6R)-1-(7-oxa-bicyclo[4.1.0]hept-1-yl)methyl ester 
• 125923-42-4 4-Methyl-N-[3-(toluene-4-sulfonyl)-propyl]-benzenesulfonamide 
• 106-45-6 para-thiocresol 
• 125943-21-7 Methanesulfonic acid 3-(toluene-4-sulfonyl)-propyl ester 
• 125993-10-4 (1R,6R)-7-oxabicyclo[4.1.0]heptan-1-ylmethanol 
• 3147-28-2 3-[(4-methylphenyl)sulfanyl]-1-propanol 
• 68276-73-3 3-((4-methylphenyl)sulfonyl)propan-1-ol 
• 4845-04-9 1-cyclohexene-1-methanol 
• 122419-44-7 N-(3-Bromo-propyl)-N-cyclohex-1-enylmethyl-4-methyl-benzenesulfonamide 
• 657-84-1 sodium tosylate 
• 57981-23-4 N-(cyclohex-1-en-1-ylmethyl)-4-methylbenzenesulfonamide 
• 122419-41-4 N-Cyclohex-1-enylmethyl-4-methyl-N-[3-(toluene-4-sulfonyl)-propyl]-benzenesulfonamide 

Downstream Products

• 122419-43-6 (5S,6S,7R)-2,5-Bis-(toluene-4-sulfonyl)-2-aza-spiro[5.5]undecan-7-ol 
• 122419-43-6 (6S,7R)-2,5-Bis-(toluene-4-sulfonyl)-2-aza-spiro[5.5]undecan-7-ol 
• 49620-06-6 (+)-nitramine 

Relevant academic research and scientific papers

ENANTIOSELECTIVE TOTAL SYNTHESIS OF (+)-NITRAMINE

A short enantioselective synthesis of the spirocyclic alkaloid (+)-Nitramine (1) is reported, the azaspiro ring system being formed via intramolecular ring-opening of the chiral epoxy sulfone 7.

STEREOCONTROLLED SYNTHESIS OF THE SPIROCYCLIC ALKALOID (+/-)-NITRAMINE

A short and completely stereocontrolled total synthesis of the title alkaloid is described, the key step being spirocyclisation of the epoxy sulfone 4.