682770-51-0

Basic information

• Product Name: ethyl 5-hydroxy-5-(4-methoxyphenyl)-3-oxopentanoate
• Synonyms: ethyl 5-hydroxy-5-(4-methoxyphenyl)-3-oxopentanoate
• CAS NO: 682770-51-0
• Molecular Weight: 266.294
• Mol File: 682770-51-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ethyl 5-hydroxy-5-(4-methoxyphenyl)-3-oxopentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-hydroxy-5-(4-methoxyphenyl)-3-oxopentanoate(682770-51-0)
• EPA Substance Registry System: ethyl 5-hydroxy-5-(4-methoxyphenyl)-3-oxopentanoate(682770-51-0)

Safety Data

• Hazardous Substances Data: 682770-51-0(Hazardous Substances Data)

Upstream product

• 848900-78-7 5-(2-Chloro-acetoxy)-5-(4-methoxy-phenyl)-3-oxo-pentanoic acid ethyl ester 
• 141-97-9 ethyl acetoacetate 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 682770-65-6 5-butyryloxy-5-(4-methoxy-phenyl)-3-oxo-pentanoic acid ethyl ester 
• 848900-78-7 5-(2-Chloro-acetoxy)-5-(4-methoxy-phenyl)-3-oxo-pentanoic acid ethyl ester 
• 848900-90-3 (5S) ethyl δ-chloroacetyloxy-δ-(p-methoxyphenyl)-β-oxo-pentanoate 
• 104858-59-5 ethyl 5-(4-methoxyphenyl)-3-oxo-4-pentenoate 
• 1198212-34-8 ethyl 2-diazo-5-hydroxy-5-(4-methoxyphenyl)-3-oxopentanoate 

Relevant articles and documents

Construction of two vicinal quaternary carbons by asymmetric allylic alkylation: Total synthesis of hyperolactone C and (-)-biyouyanagin A

Call on triple A: Palladium-catalyzed asymmetric allylic alkylation (Pd-AAA; see scheme) has enabled a concise and efficient synthesis of hyperolacto ne C and (-)-biyouyanagin A in only six (20% Overall yield) and seven (8% overall yield) steps, respectively. The enantiomers of these natural products were also prepared by exploiting the same methodology.

A Chemoenzymatic Approach to Optically Active 5-Hydroxy-3-oxocarboxylates

Enzymatic hydrolysis was applied to the preparation of certain chiral 5-hydroxy-3-oxo-carboxylates that are potential precursors for natural product synthesis via the formation of lactone derivatives and tetrahydropyran rings.