682802-01-3Relevant articles and documents
Syntheses and biological evaluation of new fluoroquinolone antibacterials containing chiral oxiimino pyrrolidine
Choi, Dong Rack,Shin, Jung Han,Yang, Jin,Yoon, Sue Hye,Jung, Yong Ho
, p. 1273 - 1277 (2007/10/03)
The design and syntheses of new fluoroquinolone antibacterial agents having pyrrolidine ring at C-7 position are described. The pyrrolidine ring is optically active and possesses methyloxime functional group. Two of them have excellent in vitro antibacterial activities and pharmacokinetic profiles.