682806-82-2

Upstream product

• 79-37-8 oxalyl dichloride 
• 263722-72-1 7,7-dimethyl-2'-phenyl-pyrazol-3'-one-bicyclo[2.2.1]heptane 

Downstream Products

• 682806-85-5 (S)-4-((1S,5R,7R)-10,10-Dimethyl-2-oxo-3-phenyl-3,4-diaza-tricyclo[5.2.1.0^1,5]dec-4-yl)-3-hydroxy-2-methylene-4-oxo-butyric acid phenyl ester 

Relevant academic research and scientific papers

Highly diastereoselective allylation and reduction of chiral camphor-derived α-ketoamides

The diastereoselective allylation and reduction of camphor-derived α-ketoamides to give optically enriched α-hydroxyl amides with high to excellent stereoselectivities are described. Allylation was carried out using allyltributylstannane in the presence o

Diastereoselective Baylis-Hillman reaction using N-glyoxyloyl camphorpyrazolidinone as an electrophile: Synthesis of optically pure 2-hydroxy-3-methylene succinic acid derivative

The camphorpyrazolidinone derived N-glyoxylate was efficiently prepared and used as an electrophile in the Baylis-Hillman reaction under classical DABCO catalyzed conditions. The corresponding 2-hydroxy-3-methylene succinic acid derivative was generally obtained with excellent diastereoselectivity and moderate chemical yields (51-75%).