68284-66-2Relevant academic research and scientific papers
Synthesis and antiarrhythmic activity of α,α-bis[(dialkylamino)- alkyl]phenylacetamides
Yonan,Novotney,Min Woo,Prodan,Hershenson
, p. 1102 - 1108 (2007/10/02)
The synthesis and biological evaluation of a series of α,α-bis[(dialkylamino)alkyl]phenylacetamides are presented. These compounds are structurally related to the antiarrhythmic agent disopyramide and in many cases were found to possess greater antiarrhyt
α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds
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, (2008/06/13)
Novel α-aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides are described herein. The compounds are useful as anti-arrhythmic agents. The compounds are prepared by reacting an appropriate disubstituted acetonitrile with an appropriate haloalkyl amine and
