68313-93-9

Upstream product

• 68314-20-5 (6R)-7c-benzoylamino-3-methyl-8-oxo-(6rH)-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 865-34-9 lithium methanolate 
• 68402-81-3 diphenylmethyl 7β-benzamido-7α-methoxy-3-<<(1-methyl-1H-yetrazol-5-yl)thio>methyl>-1-oxadethia-3-cephem-4-carboxylate 
• 106162-88-3 (2R,6R,7R)-7-Benzoylamino-7-methoxy-3-methylene-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester 
• 67977-91-7 (2R,6R,7R)-7-Benzoylamino-3-methylene-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester 
• 67977-61-1 epi-Secopenicillin 
• 68313-65-5 (2R,3Ξ)-3,4-dihydroxy-3-methyl-2-((1R)-7-oxo-3-phenyl-(1rH,5cH)-4-oxa-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-butyric acid benzhydryl ester 
• 74081-43-9 (6R)-7c-benzoylamino-3c-hydroxy-3t-methyl-8-oxo-(6rH)-5-oxa-1-aza-bicyclo[4.2.0]octane-2c-carboxylic acid benzhydryl ester 
• 73786-37-5 (6R)-7c-benzoylamino-3t-bromo-3c-methyl-8-oxo-(6rH)-5-oxa-1-aza-bicyclo[4.2.0]octane-2c-carboxylic acid benzhydryl ester 
• 68539-37-7 (2S,3S)-3-bromo-4-hydroxy-3-methyl-2-((1R)-7-oxo-3-phenyl-(1rH,5cH)-4-oxa-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-butyric acid benzhydryl ester 

Downstream Products

• 77982-90-2 (6R)-7t-amino-7c-methoxy-3-methyl-8-oxo-(6rH)-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 77930-84-8 (6R,7R)-7-(5-tert-Butoxycarbonylamino-5-carboxy-pentanoylamino)-7-methoxy-3-methyl-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 77930-79-1 (6R,7R)-7-[5-tert-Butoxycarbonylamino-5-(2,2,2-trichloro-ethoxycarbonyl)-pentanoylamino]-7-methoxy-3-methyl-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 

Relevant academic research and scientific papers

Synthesis and 3'-Substituent Effects of Some 7α-Methoxy-1-oxacephems on Antibacterial Activity and Alkaline Hydrolysis Rates

Relationships between intrinsic antibacterial activity and β-lactam chemical reactivity of 7β-(phenylacetamido)-7α-methoxy-1-oxacephems with various 3'-substituents (1-9) were studied in order to clarify the effect of the 3'-substituent on the antibacteri

SYNTHESIS OF 1-OXA ANALOGUES OF NATURALLY OCCURRING CEPHALOSPORINS AND CEPHAMYCINS

The title compounds 15a-c and 16a-c were synthesized from a 3-exomethylene-1-oxacepham compound 4.Its chlorohydroxylation provided a key intermediate 5e in synthesis of the 3'-oxygen-functionalized 1-oxacephems.