683278-53-7

Upstream product

• 41632-89-7 isobutyraldehyde dimethyl acetal 
• 683278-48-0 (4S,5S)-2,2,5-Trimethyl-4-((S)-1-methyl-allyl)-[1,3]dioxane 
• 155417-64-4 (2S,3S,4S)-2,4-Dimethylhex-5-ene-1,3-diol 
• 81470-77-1 (2S,3S,4S)-5-Benzyloxy-1,3-isopropylidenedioxy-2,4-dimethylpentane 
• 97805-14-6 (2R,3R,4S)-3,5-Isopropylidenedioxy-2,4-dimethylpentanal 
• 97805-13-5 (2S,3S,4S)-3,5-isopropylidenedioxy-2,4-dimethyl-1-pentanol 
• 106296-58-6 (2S,3S,4S)-(1-tert-butyldimethylsilanyloxy)-2,4-dimethylhex-5-en-3-ol 
• 100-39-0 benzyl bromide 
• 108393-28-8 (2S,3R,4S)-5-benzyloxy-2,3-dimethylpentane-1,4-diol 

Relevant academic research and scientific papers

Stereoselection at the Steady State in Radical Cyclizations of Acyclic Systems Containing One Radical Acceptor and Two Precursors in a 1,5- Relationship under Pseudo-First-Order Conditions

The first example of a successive kinetic resolution of acyclic diastereomeric radical intermediates in a 1,5-relationship under pseudo-first-order conditions is reported. A mechanistic model involves nonselective generation of the radical intermediates followed by different partitioning of these between two different chemical pathways. The "2,5-cis" selectivity in the radical cyclization step arises from transition geometries with the substituents aligned in pseudoequatorial positions.