6833-19-8

Basic information

• Product Name: N-phenyl-1-naphthamide
• Synonyms: N-phenyl-1-naphthamide;N-Phenyl-1-naphthalenecarboxamide;N-Phenylnaphthalene-1-carboxamide
• CAS NO: 6833-19-8
• Molecular Formula: C₁₇H₁₃NO
• Molecular Weight: 247.29122
• Mol File: 6833-19-8.mol
• Article Data: 43

Chemical Properties

• Boiling Point: 347.6°Cat760mmHg
• Flash Point: 210.2°C
• Appearance: /
• Density: 1.221g/cm³
• Vapor Pressure: 5.31E-05mmHg at 25°C
• Refractive Index: 1.705
• CAS DataBase Reference: N-phenyl-1-naphthamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-1-naphthamide(6833-19-8)
• EPA Substance Registry System: N-phenyl-1-naphthamide(6833-19-8)

Safety Data

• Hazardous Substances Data: 6833-19-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H13NO/c19-17(18-14-9-2-1-3-10-14)16-12-6-8-13-7-4-5-11-15(13)16/h1-12H,(H,18,19)

Upstream product

• 62-53-3 aniline 
• 879-18-5 naphthalene-1-carbonic acid chloride 
• 93-98-1 N-phenyl benzoyl amide 
• 7446-70-0 aluminium trichloride 
• 91-20-3 naphthalene 
• 103-71-9 phenyl isocyanate 
• 60-29-7 diethyl ether 
• 10026-13-8 phosphorus pentachloride 
• 859193-59-2 [1]naphthyl-phenyl ketone oxime 
• 66-77-3 1-naphthaldehyde 
• 890-50-6 [1]naphthylmethylen-aniline 
• 3007-97-4 ethyl 1-naphthoate 
• 85925-09-3 1-chloro-1-(thiophenoxy)-1H-cyclobutanaphthalene 
• 85924-90-9 1-(thiophenoxy)-1H-cyclobutanaphthalene 

Downstream Products

• 5892-82-0 (Naphthalene-1-carbonyl)-phenyl-carbamic acid isopropyl ester 
• 259817-02-2 methyl 2-diazo-3-[N-(1-naphthoyl)-N-phenylamino]-3-oxopropanoate 
• 83738-56-1 (4-dimethylamino-phenyl)-[1]naphthyl ketone 
• 271579-28-3 1-benzyl-2-(naphthalen-1-yl)-1H-benzo[d]imidazole 
• 1609460-32-3 N-benzyl-N′-phenyl-1-naphthimidamide 
• 544441-92-1 N-(4-bromophenyl)naphthalene-1-carboxamide 
• 1281681-11-5 1-(2-hydroxyethyl)-3-(N-phenyl-1-naphthylacetimidoyl)thiourea 
• 1281681-10-4 3-(N-phenyl-1-naphthylacetimidoyl)-1-(3-pyridylmethyl)thiourea 
• 1256360-92-5 C₂₇H₂₁NO₃ 
• 1256360-93-6 C₂₇H₁₉NO₃ 
• 1253388-58-7 C₃₁H₂₁NO 
• 1253388-59-8 C₂₅H₂₅NO 

Relevant articles and documents

Palladium-Catalyzed Annulation of Arylbenzamides with Diaryliodonium Salts

By using diaryliodonium salts, a cylization has been accomplished in the synthesis of N-aryl phenanthridinone derivatives via a cascade of ortho-arylation and Csp2-N bond formation in the presence of palladium catalyst. The reaction exhibits a broad compatibility of readily available N-arylnaphthamides. (Figure presented.).

Palladium-Catalyzed Desulfurative Hiyama Coupling of Thioureas to Achieve Amides via Selective C-N Bond Cleavage

Palladium-catalyzed Hiyama coupling of active thioureas via selective C-N bond cleavage is reported. Notably, the new approach employed active thioureas as coupling partners in the presence of arylsilanes to give amides in good yield. Further, this strategy, which utilized CuF 2as a key oxidant and activator, afforded various amide products under mild conditions and an easy to handle procedure without extra base.

Practical one-pot amidation of N -Alloc-, N -Boc-, and N -Cbz protected amines under mild conditions

A facile one-pot synthesis of amides from N-Alloc-, N-Boc-, and N-Cbz-protected amines has been described. The reactions involve the use of isocyanate intermediates, which are generated in situ in the presence of 2-chloropyridine and trifluoromethanesulfonyl anhydride, to react with Grignard reagents to produce the corresponding amides. Using this reaction protocol, a variety of N-Alloc-, N-Boc-, and N-Cbz-protected aliphatic amines and aryl amines were efficiently converted to amides with high yields. This method is highly effective for the synthesis of amides and offers a promising approach for facile amidation.