68332-33-2 Usage
General Description
3-(3-Iodo-phenyl)-3-oxo-propionic acid ethyl ester is an organic compound with the molecular formula C11H11IO3. This chemical is a derivative of propionic acid and is often used in pharmaceutical and chemical research. It is a white to off-white solid with a melting point of 141-143°C. The compound is typically synthesized through esterification of 3-(3-iodophenyl)-3-oxopropanoic acid with ethanol. It is also used as a building block in the synthesis of various pharmaceuticals and other organic compounds. Additionally, it is a potential substrate in chemical reactions such as oxidation, reduction, and acid-base reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 68332-33-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,3,3 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 68332-33:
(7*6)+(6*8)+(5*3)+(4*3)+(3*2)+(2*3)+(1*3)=132
132 % 10 = 2
So 68332-33-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H11IO3/c1-2-15-11(14)7-10(13)8-4-3-5-9(12)6-8/h3-6H,2,7H2,1H3
68332-33-2Relevant articles and documents
Amide/Ester Cross-Coupling via C-N/C-H Bond Cleavage: Synthesis of β-Ketoesters
Chen, Jiajia,Joseph, Devaneyan,Xia, Yuanzhi,Lee, Sunwoo
, p. 5943 - 5953 (2021/04/02)
Activated primary, secondary, and tertiary amides were coupled with enolizable esters in the presence of LiHMDS to obtain good yields of β-ketoesters at room temperature. Notably, this protocol provides an efficient, mild, and high chemoselectivity method
THERAPEUTIC COMPOUNDS AND USES THEREOF
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Page/Page column 71, (2015/10/05)
The present invention relates to compounds useful as inhibitors of one or more histone demethylses, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said
