68359-23-9

Upstream product

• 100-39-0 benzyl bromide 
• 609-71-2 2-hydroxy-3-carboxypyridine 
• 89960-36-1 1-benzyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid 

Downstream Products

• 863395-22-6 1,1'-dibenzyl-3,3'-(N-benzyliminodicarbonyl)di-2-pyridone 
• 863395-20-4 1,1'-dibenzyl-3,3'-(N-isopropyliminodicarbonyl)di-2-pyridone 
• 863395-21-5 1,1'-dibenzyl-3,3'-(N-butyliminodicarbonyl)di-2-pyridone 

Relevant academic research and scientific papers

Creation of concave-shaped conformation in crystal structures using an iminodicarbonyl linker. An application to solid-state intramolecular [4 + 4] photocycloaddition reactions of 2-pyridone derivatives

Single-crystal X-ray structures of 6 carboxamides possessing two units of 2-pyridone moieties connected with an iminodicarbonyl linker were examined to show the usefulness of this linker for the creation of concave-shaped conformation in crystal structure

PHARMACEUTICALLY ACTIVE BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES

Compounds of formula (I): wherein R1, R2 and R3 are independently, hydrogen, halogen, CF3, OR6, NR7R8, NR8COR10, NR8SO2R10 or C1-6 alkyl optionally substituted by hydroxy, C1-6 alkoxy or NR7R8; R4 is NR8CONR8R9, NR8COR9, NR8SO2R9, or W-CONR8R9, where W is a bond, C1-6 alkylene, C2-6 alkenylene or C2-6 alkynylene; and R5 is Formula (A) methods for their synthesis, pharmaceutical compositions comprising them and their use in medicine, in particular for the treatment of cancer.