68375-44-0

Basic information

• Product Name: 1H-Pyrazole-3-carboxamide, 4-amino-N,5-dimethyl-
• Synonyms: 1H-Pyrazole-3-carboxamide, 4-amino-N,5-dimethyl-
• CAS NO: 68375-44-0
• Molecular Formula: C₆H₁₀N₄O
• Molecular Weight: 154.1698
• Mol File: 68375-44-0.mol

Chemical Properties

• Boiling Point: 403.4°Cat760mmHg
• Flash Point: 197.8°C
• Appearance: /
• Density: 1.286g/cm³
• Vapor Pressure: 1.02E-06mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: 1H-Pyrazole-3-carboxamide, 4-amino-N,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-3-carboxamide, 4-amino-N,5-dimethyl-(68375-44-0)
• EPA Substance Registry System: 1H-Pyrazole-3-carboxamide, 4-amino-N,5-dimethyl-(68375-44-0)

Safety Data

• Hazardous Substances Data: 68375-44-0(Hazardous Substances Data)

Usage

Organic compound

It is an organic compound, meaning it is primarily composed of carbon atoms along with hydrogen, and possibly other elements such as oxygen and nitrogen.

Pyrazole structure

The compound contains a pyrazole ring, which is a five-membered heterocyclic ring with two nitrogen atoms and one oxygen atom.

Amide functional group

The presence of an amide group (-CONH2) in the molecule, which is a functional group consisting of a carbonyl group (C=O) bonded to a nitrogen atom with a hydrogen atom attached.

Amino side chain

The compound has an amino side chain (-NH2), which is a functional group consisting of a nitrogen atom with two hydrogen atoms attached.

Dimethyl side chains

The presence of two methyl groups (-CH3) attached to the nitrogen atoms in the pyrazole ring, contributing to the compound's structure.

Pharmaceutical applications

The compound may have potential applications in pharmaceuticals due to its ability to inhibit certain enzymes, making it a candidate for anti-cancer and anti-inflammatory drug development.

Organic synthesis building block

1H-Pyrazole-3-carboxamide, 4-amino-N,5-dimethylmay be used as a building block for the synthesis of more complex organic molecules.

Further research needed

More research is required to fully understand the potential applications and effects of 1H-Pyrazole-3-carboxamide, 4-amino-N,5-dimethyl-, as its properties and uses are not yet completely known.

InChI:InChI=1/C6H10N4O/c1-3-4(7)5(10-9-3)6(11)8-2/h7H2,1-2H3,(H,8,11)(H,9,10)

Upstream product

• 4027-57-0 ethyl 5-methyl-2H-pyrazole-3-carboxylate 
• 696-22-0 5-methyl-2H-pyrazole-3-carboxylic acid 
• 1352043-29-8 C₅H₄ClN₃O₃ 
• 5334-38-3 3-methyl-4-nitropyrazole-5-carboxylic acid 
• 68375-43-9 5-methyl-4-nitro-1⁽²⁾H-pyrazole-3-carboxylic acid methylamide 

Downstream Products

• 138787-09-4 C₃₂H₂₇N₅O₈ 
• 138787-06-1 C₃₂H₂₇N₅O₈ 

Relevant articles and documents

Synthesis and anti-TMV activity of novel N-(3-alkyl-1H-pyrazol-4-yl)-3- alkyl-4-substituted-1H-pyrazole-5-carboxamides

In order to investigate the biological activity of novel bis-pyrazole compounds, a series of N-(3-alkyl-5-(N-methylcarbamyl)-1H-pyrazol-4-yl)-3-alkyl- 4-substituted-1H-pyrazole-5-carboxamides were designed and synthesized with ethyl 3-alkyl-1H-pyrazole-5-

Pyrazole-Related Nucleosides. Synthesis and Antiviral/Antitumor Activity of Some Substituted Pyrazole and Pyrazolo-1,2,3-triazin-4-one Nucleosides

Several pyrazole and pyrazolo-1,2,3-triazin-4-one ribonucleosides were prepared and tested for antiviral/antitumor activities.Appropriate heterocyclic bases were prepared by standard methodologies.Glycosylation of pyrazoles 6a-e,g,i and pyrazolo-1,2,3-triazin-4-ones 12f-l mediated bu silylation with hexamethylsilazane, with 1-β-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose gave in good yields the corresponding glycosides 7a-e,g, 8g,i 13f,h,k, and 14f, but could not be applied to compounds 12g,i,j,l.To overcome this occurrence, a different strategy involvi ng the preparation, diazotization, and in situ cyclization of opportune pyrazole glycosides 9 and 10 was reguired.Moreover derivatives having the general formula 5 were considered not only as synthetic intermediates in the synthesis of 3 but also as carbon bioisosteres of ribavirin 4.All compounds were evaluated in vitro for cytostatic and antiviral activity.The pyrazolo-1,2,3-triazin-4-one nucleosides that resulted were substantially devoid of any activity; only 15h,k showed a moderate cytostatic activity against T-cells.However, pyrazole nucleosides 9b,c,e were potent and selective cytotoxic agents against T-lymphocytes, whereas 9e showed a selective, although not very potent, activity against coxsackie B1.