68404-19-3

Usage

Uses

Used in Organic Synthesis:
N,N-dipropylprop-2-enamide is used as a reactive intermediate in organic synthesis for the preparation of various chemical compounds. Its unique structure allows for versatile reactions and transformations, making it a valuable building block in the synthesis of complex organic molecules.
Used in Polymer and Plastics Production:
N,N-dipropylprop-2-enamide is also utilized in the production of polymers and plastics. Its ability to form long chains and cross-link with other monomers contributes to the development of materials with specific properties, such as strength, flexibility, and durability.
Used in Pharmaceutical Industry:
N,N-dipropylprop-2-enamide can be used as a starting material or intermediate in the synthesis of pharmaceutical compounds. Its reactivity and structural features enable the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
In the field of chemical research, N,N-dipropylprop-2-enamide serves as a model compound for studying various reaction mechanisms and exploring new synthetic methodologies. Its unique properties provide insights into the behavior of similar compounds and contribute to the advancement of chemical knowledge.

Upstream product

• 142-84-7 di-n-propylamine 
• 79-10-7 acrylic acid 
• 814-68-6 acryloyl chloride 

Downstream Products

• 1224594-05-1 3-nitro-N,N-dipropylisoxazole-5-carboxamide 
• 1224594-11-9 4,4,4-trinitro-N,N-dipropylbutanamide 
• 1114-59-6 N,N-dipropylpropionamide 

Relevant academic research and scientific papers

Clickable coupling of carboxylic acids and amines at room temperature mediated by SO2F2: A significant breakthrough for the construction of amides and peptide linkages

The construction of amide bonds and peptide linkages is one of the most fundamental transformations in all life processes and organic synthesis. The synthesis of structurally ubiquitous amide motifs is essential in the assembly of numerous important molecules such as peptides, proteins, alkaloids, pharmaceutical agents, polymers, ligands and agrochemicals. A method of SO2F2-mediated direct clickable coupling of carboxylic acids with amines was developed for the synthesis of a broad scope of amides in a simple, mild, highly efficient, robust and practical manner (>110 examples, >90% yields in most cases). The direct click reactions of acids and amines on a gram scale are also demonstrated using an extremely easy work-up and purification process of washing with 1 M aqueous HCl to provide the desired amides in greater than 99% purity and excellent yields.

(Meth) acrylamide N-substituted (by machine translation)

PROBLEM TO BE SOLVED: a (meth) acrylic acid and a starting material, high yield, high-purity (meth) and N-substituted carboxylic acid amide derivative norbonene alkylacrylamide industrial production method. SOLUTION: and (meth) acrylic acid aminopentadienoic cyclometallized Diels-Alder reaction product of, norbonene carboxylic acid derivative, and silica as a main catalyst in the presence of an inorganic material, and amide-amine compound, norbonene carboxylic acid amide derivative. Furthermore, the vapor phase of the norbonene vinylcarboxamide deriv. aminopentadienoic cyclometallized by thermal decomposition reaction by desorbing, (meth) acrylamide purpose compd. N-substituted. Selected drawing: no (by machine translation)

METHOD FOR PRODUCING N-SUBSTITUTED (METH)ACRYLAMIDE

PROBLEM TO BE SOLVED: To provide an industrial method for efficiently producing a high-purity N-substituted (meth)acrylamide in a short time even under mild reaction conditions, which uses (meth)acrylic acid as a starting material and generates only water as a byproduct. SOLUTION: There is provided a method for producing an N-substituted (meth)acrylamide to obtain an objective compound, N-substituted (meth)acrylamide by the step of: reacting a (meth)acrylic and an amine compound to synthesize an aminopropionic acid derivative; then adding an inorganic material composed mainly of silica as a catalyst and performing amidation with the same amine compound to obtain an aminopropionic acid derivative; and subsequently eliminating an amine by the thermal decomposition reaction. COPYRIGHT: (C)2015,JPOandINPIT

Unexpected heterocyclization of electrophilic alkenes by tetranitromethane in the presence of triethylamine. Synthesis of 3-nitroisoxazoles

Novel reaction of tetranitromethane (TNM) with electrophilic alkenes in the presence of triethylamine yielding substituted 3-nitroisoxazoles was found and studied. Triethylamine increases the reactivity of TNM toward electrophilic alkenes promoting their heterocyclization, and the reactions proceed in an unusual way. A variety of α,β-unsaturated aldehydes, ketones, esters, amides, phosphonates, and nitro and sulfur compounds was involved in the heterocyclization reaction, and a wide range of functionalized 3-nitroisoxazoles was obtained in good to high yields. The scope and limitations of the reaction and the mechanistic aspects are discussed.