68406-57-5

Basic information

• Product Name: N-(1H-benzimidazol-2-ylsulfanyl)cyclohexanamine
• CAS NO: 68406-57-5
• Molecular Formula: C₁₃H₁₇N₃S
• Molecular Weight: 247.3592
• Mol File: 68406-57-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 442.4°C at 760 mmHg
• Flash Point: 221.3°C
• Density: 1.24g/cm³
• Vapor Pressure: 5.04E-08mmHg at 25°C
• Refractive Index: 1.661
• CAS DataBase Reference: N-(1H-benzimidazol-2-ylsulfanyl)cyclohexanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1H-benzimidazol-2-ylsulfanyl)cyclohexanamine(68406-57-5)
• EPA Substance Registry System: N-(1H-benzimidazol-2-ylsulfanyl)cyclohexanamine(68406-57-5)

Safety Data

• Hazardous Substances Data: 68406-57-5(Hazardous Substances Data)

Usage

General Description

N-(1H-benzimidazol-2-ylsulfanyl)cyclohexanamine, also known as rabeprazole, is a chemical compound used as a proton pump inhibitor (PPI) medication to decrease the amount of acid produced in the stomach. It works by blocking the enzyme that produces acid in the stomach, providing relief from conditions such as gastroesophageal reflux disease (GERD), ulcers, and other gastrointestinal conditions. Rabeprazole is typically taken orally in the form of delayed-release tablets, and its effects can last for up to 24 hours. It is considered to be a safe and effective medication when used as prescribed by a healthcare professional, but may have potential side effects such as headache, nausea, and diarrhea.

Upstream product

• 538-75-0 dicyclohexyl-carbodiimide 
• 108-91-8 cyclohexylamine 
• 87504-17-4 2-cyclohexylbenzimidazo<1,2-d><1,2,4>thiadiazol-3(2H)-one 
• 98154-63-3 2-ethyl-1,2,4-thiadiazolo[4,5-a]benzimidazole-3(2H)-one 

Relevant articles and documents

Exchange, Elimination, and Ring Opening Reactions of 2,3-Dihydrobenzimidazothiadiazoles and 3H-Benzimidazodithiazoles

The reactions of benzimidazothiadiazol-3(2H)-ones (1) with isocyanates, isothiocyanates, carbon disulphide, aryl cyanates, acetylenedicarboxylates, and enamines, with exchange of the isocyanate component of (1), to give the corresponding condensed benzimidazole derivatives (1)-(6) are described.Under more severe conditions the 1-benzothiazol-2-yl-1,3-dihydrobenzimidazole-2-thiones (7) were obtained from aromatic isothiocyanates.Thermolysis of the thiadiazoles (1) led to the triazine derivative (12) with elimination of isocyanate and sulphur, and in the presence of phenols to the 2-aryloxybenzimidazoles (13).With amines and CH-acidic compounds, the S,N bond in compound (1) was cleaved to give benzimidazol-2-ylsulphenamides (14), and the ω-substituted methylthiobenzimidazoles (17) and (18).With cyanide ion, insertion into the S,N bond of compound (1) to furnish the thiadiazine (22) took place.The dithiazoles (2) were fragmented by amines to give 1,3-dihydrobenzimidazole-2-thione and guanidine with loss of sulphur; reaction with cyanide ion then gave the dibenzimidazothiadiazine (25).