68423-18-7Relevant academic research and scientific papers
Electrophilic Trifluoromethylthiolation/Semipinacol Rearrangement: Preparation of β-SCF3 Carbonyl Compounds with α-Quaternary Carbon Center
Xi, Chao-Chao,Chen, Zhi-Min,Zhang, Shu-Yu,Tu, Yong-Qiang
, p. 4227 - 4230 (2018/07/29)
A new and modular electrophilic trifluoromethylthiolation/semipinacol rearrangement of allylic silyl ethers has been developed under mild conditions. This approach allows the formation of a number of β-SCF3 carbonyl compounds with a cyclic and all-carbon quaternary center framework in moderate to good yields. It should be noted that this achievement is a metal-free process and just requires the use of simple acetyl chloride as an acidic promoter. Additionally, an interesting H-migration in competition with aryl-migration process was revealed.
Dual visible light photoredox and gold-catalyzed arylative ring expansion
Shu, Xing-Zhong,Zhang, Miao,He, Ying,Frei, Heinz,Toste, F. Dean
supporting information, p. 5844 - 5847 (2014/05/20)
A combination of visible light photocatalysis and gold catalysis is applied to a ring expansion-oxidative arylation reaction. The reaction provides an entry into functionalized cyclic ketones from the coupling reaction of alkenyl and allenyl cycloalkanols with aryl diazonium salts. A mechanism involving generation of an electrophilic gold(III)-aryl intermediate is proposed on the basis of mechanistic studies, including time-resolved FT-IR spectroscopy.
