68423-19-8Relevant academic research and scientific papers
Electrophilic addition of allylic carbocations to 2-cyclopropylidene-2- arylethanols: A strategy to 3-oxabicyclo[3.2.0]heptanes
Meng, Bo,Huang, Xian,Wu, Luling
, p. 2637 - 2650 (2013/10/21)
We have developed an electrophilic addition of allylic carbocations to 2-cyclopropylidene-2-arylethanols constructing carbon-carbon bonds with excellent regio- and stereoselectivities. The reaction affords 3-oxabicyclo[3.2.0]heptanes in moderate to good y
A Concise and Enantioselective Approach to Cyclobutanones by Tandem Asymmetric Epoxidation and Enantiospecific Ring Expansion of Cyclopropylidene Alcohols. An Enantiocontrolled Synthesis of (+)- and (-)-α-Cuparenones
Nemoto, Hideo,Ishibashi, Hiroki,Nagamochi, Masatoshi,Fukumoto, Keiichiro
, p. 1707 - 1712 (2007/10/02)
A tandem Katsuki-Sharpless asymmetric epoxidation and enantiospecific ring expansion of 2-alkyl(or 2-aryl)-2-cyclopropylideneethanols (1a-i) afforded chiral 1-alkyl(or 1-aryl)-1-(hydroxymethyl)cyclobutanones (3a-i) in high yields and high enantiomeric excess.These compounds are potentially valuable synthons for the enantioselective creation of the quaternary carbons.Hence, this enabled us to accomplish a concise and enantioselective total synthesis of both (+)- and (-)-cuparenones (11).
