68433-32-9

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 68433-31-8 (C₆H₅)3PNP(C₆H₅)3⁽¹⁺⁾*(CO)4MnCOCH(C₆H₅)OCO^(1-)=(C₆H₅)3PNP(C₆H₅)3(CO)4MnCOCH(C₆H₅)OCO 
• 100-52-7 benzaldehyde 
• 68433-34-1 (CO)5MnCH(C₆H₅)OSi(CH₃)3 

Downstream Products

• 16972-33-1 pentacarbonylhydridomanganese 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

Reactions of (CO)5MnSi(CH3)3 and CO with aldehydes and cyclic ethers. Syntheses of functionalized pentacarbonylmanganese acyls and homologated organic compounds

Reactions of (CO)5MnSi(CH3)3 (1) and CO with aldehydes RCHO and cyclic ethers OCH2(CH2)nCH2 (n = 0-2) give manganese acyls (CO)5MnCOCH(R)OSi(CH3)3 and (CO)5MnCOCH2(CH2)nCH 2OSi(CH3)3 (n = 0, 6; n = 1, 9; n = 2, 10) in 26-72% and 54-87% yields, respectively. Experiments conducted in the absence of CO show that these transformations proceed via labile alkyl intermediates (CO)5MnCH(R)OSi(CH3)3 and (CO)5MnCH2(CH2)nCH 2OSi(CH3)3. Reactions of propylene oxide and cyclohexene oxide with 1 and CO give the manganese acyls expected from SN2 ring opening. When the reaction of 1 with aldehydes is conducted in the presence of (CO)5MnH under careful conditions, homologated aldehydes (CH3)3SiOCHRCHO form in 55-78% yields. Reaction of 1 and (CO)5MnH with oxetane gives (CH3)3-SiOCH2CH2CH2CHO (13, 38%) and (CH3)3SiOCHCH2CH2CH2O (14, 59%). Reaction of 9 and 10 with [(CH3CH2)2N]3S+Si(CH 3)3F2- yields γ-butyrolactone (84-95%) and δ-valerolactone (60-85%), respectively. The mechanisms of these transformations, and their utility in organic and organometallic synthesis, are discussed.