68462-57-7

Usage

Uses

Used in Organic Synthesis:
4-Nitrophenyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside is used as a synthetic intermediate for the preparation of various complex organic molecules. Its unique structure allows it to serve as a building block in the synthesis of biologically active compounds, pharmaceuticals, and other specialty chemicals.
Used in Glycochemistry Research:
In the field of glycochemistry, 4-Nitrophenyl2-O-(a-D-mannopyranosyl)-a-D-mannopyranoside is employed as a substrate to study the enzymatic activity of glycosidases and other enzymes involved in carbohydrate metabolism. It aids researchers in understanding the mechanisms of these enzymes and their role in various biological processes.
Used in Analytical Chemistry:
4-Nitrophenyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside is also utilized in the development of analytical methods for detecting and quantifying glycosidase activity. Its chromophoric nitrophenyl group allows for easy monitoring of enzymatic reactions, making it a valuable tool in assay development.
Used in Drug Discovery:
As a compound with potential biological activity, 4-Nitrophenyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside may be used in drug discovery efforts to identify new therapeutic agents. Its unique structure could provide insights into the design of novel drugs targeting carbohydrate-related diseases or conditions.

InChI:InChI=1/C18H25NO13/c20-5-9-11(22)13(24)15(26)17(30-9)32-16-14(25)12(23)10(6-21)31-18(16)29-8-3-1-7(2-4-8)19(27)28/h1-4,9-18,20-26H,5-6H2/t9-,10-,11-,12-,13+,14+,15+,16+,17-,18+/m1/s1

Upstream product

• 10357-27-4 4-nitrophenyl-α-D-mannopyranoside 
• 2492-87-7 p-nitrophenyl β-D-mannopyranoside 
• 79580-52-2 p-nitrophenyl 3-O-benzoyl-4,6-di-O-benzylidene-α-D-mannopyranoside 
• 93979-04-5 p-nitrophenyl 3-O-benzoyl-4,6-O-benzylidene-2-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-α-D-mannopyranoside 
• 210281-95-1 β-D-mannopyranosyl fluoride 
• 439-03-2 2,3,4,6-tetra-O-acetyl-β-D-mannopyranosyl fluoride 
• 14218-11-2 2,3,4,6-Tetra-O-benzoyl-α-D-mannopyranosyl bromide 

Relevant academic research and scientific papers

Creation of an α-mannosynthase from a broad glycosidase scaffold

α-Mannosides made easy: Mutation of a family-GH31 α-glucosidase that displays plasticity to alterations at the 2-OH position of donor substrates created an efficient α-mannoside-synthesizing biocatalyst. A simple fluoride donor reagent was used for the synthesis of a range of mono-α-mannosylated conjugates using the α-mannosynthase displaying low (unwanted) oligomerization activity. Copyright

A SIMPLE STRATEGY FOR CHANGING THE REGIOSELECTIVITY OF GLYCOSIDASE-CATALYSED FORMATION OF DISACCHARIDES

The regioselectivity of glycosidase-catalysed formation of disaccharides can be changed by using α- or β-glycosyl acceptors with various aglycons.The preponderant formation of other than (1->6) linkages can be effected with glycosidases which normally give (1->6) linkages.Thus, an α-D-galactosidase can be induced to catalyse the formation mainly of α-(1->2)-, α-(1->3)-, or α-(1->6)-linked digalctosides.Both the structure of the aglycon and the configuration of the glycosidic linkage can have a pronounced influence on the regioselectivity of disaccharide formation.Enzymic syntheses, in yields of 20-30percent, are described of α-D-Galp-(1->3)-α-D-Galp-OMe, β-D-Galp-(1->3)-β-D-Galp-OMe, β-D-Galp-(1->6)-α-D-Galp-OMe, α-D-Manp-(1->2)-α-D-Manp-OMe, α-D-Manp-(1->6)-α-D-Manp-OMe, α-D-Galp-(1->2)-α-D-Galp-OPhNO2-o, α-D-Galp-(1->3)-α-D-Galp-OPhNO2-p, α-D-Manp-(1->2)-α-D-Manp-OPhNO2-p, and α-D-Manp-(1->2)-α-D-Manp-(1->2)-α-D-Manp-OMe.Soluble and immobilised enzymes have been used.

p-NITROPHENYL 2-, AND 3-O-α-D-MANNOPYRANOSYL-α-D-MANNOPYRANOSIDE

p-Nitrophenyl 3- and 2-O-benzoyl-4,6-O-benzylidene-α-D-mannopyranoside were each condensed with 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl bromide, and the products were deprotected, to yield, respectively, p-nitrophenyl 2- and 3-O-mannopyranosyl-α-D-mann