79580-52-2

Upstream product

• 61169-00-4 p-nitrophenyl 4,6-O-benzylidene-β-D-glucopyranoside 
• 98-88-4 benzoyl chloride 
• 100-52-7 benzaldehyde 
• 83167-72-0 p-nitrophenyl 3-O-benzoyl-β-D-galactopyranoside 
• 3150-24-1 4-nitrophenyl-β-D-galactopyranoside 
• 80321-94-4 p-nitrophenyl 3-O-benzoyl-4,6-O-isopropylidene-β-D-galactopyranoside 
• 873848-18-1 p-nitrophenyl 4,6-O-benzylidene-β-D-galactopyranoside 

Downstream Products

• 79580-53-3 p-nitrophenyl 3-O-benzoyl-4,6-O-benzylidene-2-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-β-D-galactopyranoside 
• 79580-53-3 p-nitrophenyl 3-O-benzoyl-4,6-O-benzylidene-2-O-(2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-β-D-galactopyranoside 
• 83167-77-5 p-nitrophenyl 2-O-β-D-galactopyranosyl-β-D-galactopyranoside 
• 83167-78-6 p-nitrophenyl 2-O-α-D-galactopyranosyl-β-D-galactopyranoside 
• 83167-79-7 p-nitrophenyl 4,6-benzylidene-2-O-β-D-galactopyranosyl-β-D-galactopyranoside 
• 83167-79-7 p-nitrophenyl 4,6-benzylidene-2-O-α-D-galactopyranosyl-β-D-galactopyranoside 
• 93979-04-5 p-nitrophenyl 3-O-benzoyl-4,6-O-benzylidene-2-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-α-D-mannopyranoside 
• 88493-78-1 p-nitrophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1->4)-O-3,6-di-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->2)-O-3-O-benzoyl-4,6-di-O-benzylidene-α-D-mannopyranoside 
• 16790-33-3 p-nitrophenyl 2-O-α-D-mannopyranosyl-α-D-mannopyranoside 
• 88493-79-2 p-nitrophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1->4)-O-2-acetamido-3,6-di-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->2)-O-3-O-acetyl-4,6-di-O-benzylidene-α-D-mannopyranoside 
• 88493-80-5 p-nitrophenyl O-β-D-galactopyranosyl-(1->4)-O-2-acetamido-2-deoxy-β-D-glucopyranosyl-(1->2)-α-D-mannopyranoside 
• 136963-29-6 tert-butyl uronate 
• 136963-27-4 p-nitrophenyl 3-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-2-azido-4-O-benzoyl-6-O-tert-butyldimethylsilyl-2-deoxy-β-D-mannopyranoside 
• 136963-28-5 Benzoic acid (2R,3S,4R,5S,6S)-5-azido-4-((2R,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-acetylamino-tetrahydro-pyran-2-yloxy)-2-hydroxymethyl-6-(4-nitro-phenoxy)-tetrahydro-pyran-3-yl ester 

Relevant academic research and scientific papers

Synthesis of an artificial antigen that corresponds to a disaccharide repeating unit of the capsular polysaccharide of Haemophilus influenzae type d. A facile synthesis of methyl 2-acetamido-2-deoxy-β-D-mannopyranoside

The synthesis is described of p-nitrophenyl 2-acetamido-3-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-deoxy-β- D-mannopyranosiduronic acid, corresponding to the disaccharide repeating unit of the capsular polysaccharide of Haemophilus influenzae type d, which, after conversion of the p-nitro- into a p-amino-phenyl residue, may be attached to a protein to make an artificial antigen for immunological studies. The synthesis incorporates a facile route to the 2-acetamido-2-deoxy-β-D-mannopyranosyl unit. The synthesis of p-nitrophenyl 2-acetamido-3-O- (2-acetamido-2-deoxy-β-D- glucopyranosyl) -2-deoxy -β-D-mannopyranosiduronic acid, corresponding to the disaccharide repeating unit of the capsular polysaccharide of Haemophilus influenzae type d, is described. This acid, after conversion of the p-nitro- into a p-amino-phenyl residue, may be attached to a protein to make an artificial antigen for immunological studies. The synthesis incorporates a facile route to the 2-acetamido-2 -deoxy-β-D-mannopyranosyl unit.

SYNTHESIS OF P-NITROPHENYL 2-O-β- AND 2-O-α-D-GALACTOPYRANOSYL-β-D-GALACTOPYRANOSIDE

Cleavage of the isopropylidene group of p-nitrophenyl 3-O-benzoyl-4,6-O-isopropylidene-β-D-galactopyranoside afforded p-nitrophenyl 3-O-benzoyl-β-D-galactopyranoside (1).Compound 1 was converted into its 4,6-O-benzylidene derivative (2) by reaction with t