68496-74-2 Usage
Chemical class
1,3,4-oxadiazole 1,3,4-Oxadiazole-2-carboxamide, 5-phenyl- belongs to the 1,3,4-oxadiazole class of molecules, which are characterized by a five-membered ring containing two nitrogen atoms and one oxygen atom.
Medical use
Diuretic Furosemide is used to treat fluid retention and swelling caused by congestive heart failure, liver disease, kidney disease, and high blood pressure.
Mechanism of action
Causes the kidneys to remove unneeded water and salt Furosemide works by increasing the amount of water and salt excreted by the kidneys, which helps to reduce fluid buildup in the body.
Structure
Phenyl group attached to the oxadiazole ring Furosemide has a phenyl group attached to the oxadiazole ring, which may contribute to its pharmacological properties.
Effectiveness
Widely used and effective medication Furosemide is a widely used and effective medication in the treatment of various conditions related to fluid retention.
Solubility
Generally, 1,3,4-oxadiazoles are known to be relatively polar and can be soluble in polar solvents like water and alcohol.
Synthesis
Furosemide can be synthesized through various methods, often involving the formation of the oxadiazole ring and subsequent attachment of the phenyl group.
Side effects
As with any medication, Furosemide may cause side effects, which can include dehydration, electrolyte imbalances, and hearing loss. It is essential to follow medical advice and monitor for any adverse effects while taking the medication.
Check Digit Verification of cas no
The CAS Registry Mumber 68496-74-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,4,9 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 68496-74:
(7*6)+(6*8)+(5*4)+(4*9)+(3*6)+(2*7)+(1*4)=182
182 % 10 = 2
So 68496-74-2 is a valid CAS Registry Number.
68496-74-2Relevant academic research and scientific papers
Preparation of 1,3,4-Oxadiazol-2-carboxylic Acid Derivatives
Dost, J.,Heschel, M.,Stein, J.
, p. 109 - 116 (2007/10/02)
The synthesis of 5-substituted-1,3,4-oxadiazol-2-carboxylic acid derivatives 3a-g and 4a-g by cyclodehydratation of diacylhydrazines 1a-g and 2a-g are described.Further derivatives 6 to 9 are obtained from 1,3,4-oxadiazol-2-carboxethyl esters 3.
