685094-07-9Relevant academic research and scientific papers
1,3-SUBSTITUED PYRAZOLE COMPOUNDS USEFUL FOR REDUCTION OF VERY LONG CHAIN FATTY ACIC LEVELS
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Paragraph 299, (2018/06/30)
Disclosed are chemical entities which are compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein Formula (I) has the structure: R1a, R1b, R2, R3, R4a, R4b and Y are as defined herein. These chemical entities are useful for reduction of very long chain fatty acid levels. These chemical entities and pharmaceutically acceptable compositions comprising such chemical entities can be useful for treating various diseases, disorders and conditions, such as adrenoleukodystrophy (ALD).
NITROGEN-CONTAINING HETEROARYL DERIVATIVES
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Page/Page column 23, (2011/08/06)
The invention is concerned with novel nitrogen-containing heteroaryl derivatives of formula (I) wherein R1, R2, R3, R4, R5, A1, A2, and Y are as defined in the description and in
NITROGEN-CONTAINING HETEROARYL DERIVATIVES
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Page/Page column 58, (2011/08/08)
The invention is concerned with novel nitrogen-containing heteroaryl derivatives of formula (I) wherein R1, R2, R3, R4, R5, A1, A2, and Y are as defined in the description and in
Practical synthesis of a neuropeptide Y antagonist via stereoselective addition to a ketene
Iida, Takehiko,Satoh, Hiroki,Maeda, Kenji,Yamamoto, Yuhei,Asakawa, Ken-Ichi,Sawada, Naotaka,Wada, Toshihiro,Kadowaki, Chie,Itoh, Takahiro,Mase, Toshiaki,Weissman, Steven A.,Tschaen, Dave,Krska, Shane,Volante
, p. 9222 - 9229 (2007/10/03)
The synthesis of neuropeptide Y antagonist 1, currently under clinical investigation for the treatment of obesity, is described. The convergent synthesis from trans-spirolactone carboxylic acid intermediate 2a and aminopyrazole 3 is predicated on a stereo
PROCESS FOR MAKING PYRAZOLE COMPOUNDS
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Page 48-49, (2008/06/13)
This invention relates to a process for making pyrazole compoundsof formula I.
