68532-63-8

Upstream product

• 111-81-9 Methyl 10-undecenoate 
• 24724-07-0 methyl 11-hydroxyundecanoate 
• 2834-05-1 11-bromoundecanoic acid 
• 57467-59-1 2E,5E,10-undecatrien-1-oic acid methyl ester 
• 6287-90-7 11-bromo-undecanoic acid methyl ester 
• 603-35-0 triphenylphosphine 
• 74198-06-4 methyl 11-hydroxyundeca-2E,5E-dienoate 

Downstream Products

• 1191301-94-6 C₂₁H₃₂O₄ 
• 5129-59-9 methyl 13-methyltetradecanoate 
• 2485-71-4 13-methyltetradecanoic acid 
• 88336-80-5 12-phenyl-1-dodecanol 
• 38795-65-2 ω-phenyl dodecanoic acid methyl ester 
• 106484-83-7 phenyl-laurylaldehyde 
• 6186-98-7 (Z)-11-octadecen-1-yl acetate 
• 20711-10-8 (Z)-11-tetradecenyl acetate 
• 34010-21-4 (Z)-11-hexadecen-1-yl acetate 
• 62972-93-4 (Z)-octadec-11-en-1-ol 
• 56683-54-6 (Z)-11-hexadecen-1-ol 
• 34010-15-6 cis-11-tetradecen-1-ol 
• 503868-08-4 C₂₂H₄₄NO₄P 

Relevant academic research and scientific papers

Total synthesis of (+)- and (-)-duryne: A potent anticancer agent from the marine sponge cribrochalina dura. Establishment of the central double bond geometry and the absolute configuration of the chiral centers

(Chemical Equation Presented) Duryne is a C30 polyacetylenic alcohol with C2 symmetry. Despite its potent cytotoxicity, its central double bond geometry and the absolute configuration of the chiral centers were not determined. We report the total synthese

IDEBENONE COMPOUNDS

The present application provides idebenone derivatives or analogues useful for treating a disease or disorder in a subject in need thereof. Pharmaceutical compositions comprising the compounds and methods of treating the disease or disorder are also provided.

Expansion of the structure-activity relationship of branched chain fatty acids: Effect of unsaturation and branching group size on anticancer activity

Branched chain fatty acids (BCFAs) are a class of fatty acid with promising anticancer activity. The BCFA 13-methyltetradecanoic acid (13-MTD) inhibits tumour growth in vivo without toxicity but efficacy is limited by moderate potency, a property shared b

In the optically-multiplexed-

A method for optical super-multiplexing using polyynes to provide enhanced images from stimulated Raman microscopy is disclosed. In some exemplary embodiments, the polyynes are organelle-targeted or spectral barcoded. Imaging can be enhanced by using the polyynes to image whole live cells or specific organelles within live cells. The polyynes can also be used in optical data storage (i.e., encoding) and identification (i.e., decoding) applications.

An expedient synthesis of 5-n-alkylresorcinols and novel 5-n-alkylresorcinol haptens

The first synthesis of bioactive long alkyl chain 5-n-alkylresorcinols, present in whole grain products, by a novel modification of the Wittig reaction is described. All the main long chain 5-n-alkylresorcinols present in rye and wheat, including C23 and C25 analogues and haptens, which have not been previously prepared, were synthesised. Microwave-promoted reactions of a semistabilized ylid and alkanals in water gave good yields in both pressurized and open systems. An alternative microwave-promoted synthesis starting from non-stabilized alkyltriphenylphosphonium salts and 3,5-dimethoxybenzaldehyde worked as well. Aqueous media were suitable for the reactions even if the starting materials were not soluble in water. The 5-n-alkylresorcinols are potential biomarkers of whole grain intake, and the new hapten derivatives of 5-n-alkylresorcinols will open the way for the immunochemical detection techniques of alkylresorcinols.

An easy access to symmetrical Z-olefins from phosphorus ylides

Symmetrical Z-olefins are obtained in good to quantitative yields from phosphonium salts via an autoxidation process, in salt-free conditions.

SYNTHESIS OF PHEROMONES, IV. CHEMISTRY OF THE WITTIG REACTION, I. EFFECTS OF REACTION CONDITIONS ON THE STEREOSELECTIVITY AND YIELD OF THE WITTIG REACTION

The reactions of nonstabilized triphenylphosphorus ylides with aldehydes have been studied in detail.The stereochemistry and yields of the alkene products are highly dependent upon base used for the generation of the ylide, the solvent and reaction temperature.The synthesis of sex pheromone components by Wittig reaction are also described.

INSECT PHEROMONES AND THEIR ANALOGS III. SYNTHESIS OF THE SEX ATTRACTANTS OF SOME LEPIDOPTERA

A new route to the synthesis of a number of attractants of Lepidoptera (Argyrotaenia velutinana, Mamestra configurata, and Lycorea ceres ceres) have been developed.These substances are acetates of enols with the cis configuration: tetradec-11-en-1-ol, hexadec-11-en-1-ol, and octadec-11-en-1-ol, respectively.The constants of the substances obtained agree completely with those given in the literature.The method is based on the coupling of the C3, C5, and C7 aldehydes with methyl 11-bromoundecanoate (I) by the Wittig reaction.To obtain compound (I) from methyl undeca-2E,5E,10-trienoate or methyl undeca-10-enoate we used hydroboration according to Brown followed by hydrogenation and bromination of the alcohol obtained.The advantage of this method is the use as starting materials of esters of unsaturated acids readily obtained by the homogeneous catalytic co-oligomerization of 1,3-dienes with acrylates.