68535-51-3Relevant academic research and scientific papers
Synthesis of 2-Substituted 1,2,3-Triazoles via an Intramolecular N–N Bond Formation
Chen, Cheng-yi,Lu, Xiaowei,Holland, Mareike C.,Lv, Shichang,Ji, Xuebao,Liu, Wei,Liu, Jie,Depre, Dominique,Westerduin, Pieter
, p. 548 - 551 (2019/12/24)
An efficient synthesis of 2-aryl 1,2,3-triazoles based on an intramolecular N–N bond formation is described. Selective activation of bis-hydrazone at the dimethylamino hydrazone group with MeI forms a mono-hydrazonium species. Treatment of the hydrazonium
N-terminal strategy (N1-N4) toward high performance liquid crystal materials
Hong, Fengying,Xia, Zhengce,Zhu, Dezhao,Wu, Hongxiang,Liu, Jianhui,Zeng, Zhuo
supporting information, p. 1285 - 1292 (2017/02/15)
Liquid crystal materials have a variety of applications in many fields such as display techniques as well as photonics and optics. However, only few design principles have been disclosed on liquid crystal materials with different N-heterocycles as the terminal groups, which hinder the development of the heterocyclic liquid crystals. Here, a strategy of molecular design for N-heterocyclic liquid crystal materials is reported. On the basis of this strategy, a series of convenient N-heterocycles such as pyrrole, pyrazole, imidazole, 1,2,3-triazole, 1,2,4-triazole, 1,2,3,4-tetrazole were applied to synthesize the novel liquid crystals. Most of them have proved to exhibit good mesomorphic behaviors which make them excellent components in the mixture of the LCDs materials. The simple attachment of N-heterocyclic units to the liquid crystal molecules through a mild reaction condition will provide a good prospect for the design of N-heterocyclic liquid crystals.
An easy arylation of 2-substituted 1,2,3-triazoles
Shi, Suping,Liu, Wei,He, Ping,Kuang, Chunxiang
supporting information, p. 3576 - 3580 (2014/06/09)
A selective, efficient and catalytic ligand-free method for the direct arylation of 2-aryl-1,2,3-triazoles via Pd-catalyzed C-H bond activation is described. The process smoothly proceeds in moderate to excellent yields. This journal is the Partner Organisations 2014.
Palladium-catalyzed acyloxylation of 2-substituted 1,2,3-triazoles via direct sp2 C-H bond activation
Wang, Zechao,Kuang, Chunxiang
supporting information, p. 1549 - 1554 (2014/06/09)
The palladium-catalyzed acyloxylation of 2-substituted 1,2,3-triazoles with acids via direct sp2 C-H bond activation is described. This reaction is applied to a wide variety of 2-substituted 1,2,3-triazoles and exhibits excellent functional group tolerance. The route is found to be efficient for the preparation of 2-substituted 1,2,3-triazole derivatives.
Regioselective halogenation of 2-substituted-1,2,3-triazoles via sp 2 C-H activation
Tian, Qingshan,Chen, Xianmin,Liu, Wei,Wang, Zechao,Shi, Suping,Kuang, Chunxiang
supporting information, p. 7830 - 7833 (2013/11/19)
A highly regioselective halogenation of 2-substituted-1,2,3-triazoles was developed via sp2 C-H activation. This method is compatible with halogen atoms, as well as electron-donating and electron-withdrawing groups. Meanwhile, the strategy is a
Deproto-metallation and computed CH acidity of 2-aryl-1,2,3-triazoles
Chevallier, Floris,Blin, Thomas,Nagaradja, Elisabeth,Lassagne, Frédéric,Roisnel, Thierry,Halauko, Yury S.,Matulis, Vadim E.,Ivashkevich, Oleg A.,Mongin, Florence
scheme or table, p. 4878 - 4885 (2012/07/28)
2-Aryl-1,2,3-triazoles were synthesized by cyclization of the corresponding glyoxal arylosazones, generated from commercial arylhydrazines. The deproto-metallation of 2-phenyl-1,2,3-triazole was attempted using different 2,2,6,6-tetramethylpiperidino-based mixed lithium-metal (Zn, Cd, Cu, Co, Fe) combinations, giving results in the case of Zn, Cd, and Cu. The lithium-zinc combination was next selected to apply the deprotonation-iodination sequence to all the 2-aryl-1,2,3-triazoles synthesized. The results were analyzed with the help of the CH acidities of the substrates, determined in THF solution using the DFT B3LYP method.
Highly N2-selective palladium-catalyzed arylation of 1,2,3-triazoles
Ueda, Satoshi,Su, Mingjuan,Buchwald, Stephen L.
supporting information; experimental part, p. 8944 - 8947 (2011/10/19)
A familiar ring? Highly N2-selective arylation of 4,5-unsubstituted and 4-substituted 1,2,3-triazoles was achieved for the first time by the Pd/1 catalyst system. A wide range of N2-aryl-1,2,3- triazoles were prepared from aryl bromi
