68535-58-0

Upstream product

• 96-50-4 2-thiazolylamine 
• 100-66-3 methoxybenzene 
• 288-47-1 1,3-thiazole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 696-62-8 para-iodoanisole 
• 129972-93-6 C₁₁H₁₁NO₄ 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 1086111-09-2 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-1,3-thiazole 
• 3034-55-7 5-bromo-1,3-thiazole 
• 5720-07-0 4-methoxyphenylboronic acid 

Downstream Products

• 434-90-2 decafluorobiphenyl 
• 1398310-32-1 5-(4-methoxyphenyl)-2-(perfluorophenyl)thiazole 
• 1388625-52-2 2-(5-(4-methoxyphenyl)thiazol-2-yl)benzothiazole 
• 1388625-46-4 2-(5-(4-methoxyphenyl)thiazol-2-yl)benzoxazole 
• 1339019-89-4 (E)-5-(4-methoxyphenyl)-2-(oct-4-en-4-yl)thiazole 
• 602298-60-2 3,4-O-isopropylidene-1,6-di-O-(4-thiazol-5-yl-phenyl)-D-mannitol 
• 1000029-31-1 5-(4-methoxyphenyl)-2-(4-trifluoromethylphenyl)thiazole 
• 72997-55-8 5-(4-methoxyphenyl)-2-(4-methylphenyl)thiazole 
• 68004-04-6 5-(4-methoxyphenyl)-2-phenyl-1,3-thiazole 
• 1373612-11-3 2-butylsulfanyl-5-(4-methoxyphenyl)thiazole 

Relevant academic research and scientific papers

Dehydration Polymerization for Poly(hetero)arene Conjugated Polymers

The lack of scalable and sustainable methods to prepare conjugated polymers belies their importance in many enabling technologies. Accessing high-performance poly(hetero)arene conjugated polymers by dehydration has remained an unsolved problem in syntheti

Colourless p-phenylene-spaced bis-azoles for luminescent concentrators

We report on the synthesis of new push-pull imidazole-benzothiazole and thiazole-benzothiazole fluorophores obtained in good yields by using direct C-H arylation synthetic strategies. Spectroscopic investigations in CHCl3 solution evidenced that the 1,4-phenylene-spaced imidazole-benzothiazole bearing an electron-donating dimethylamino group achieved a trade-off between fluorescence maximum (516 nm), Stokes shift (165 nm) and a quantum yield higher than 0.4. Dispersions of the selected fluorophore in poly (methyl methacrylate) (PMMA) thin films mostly maintained the optical features in solution with significant light transmittance in the visible region (90% at 440 nm), and a brilliant green emission at 500 nm. Photocurrent experiments performed on PMMA thin films coated over high purity transparent glasses promoted their use in the development of colourless luminescent solar concentrators with optical efficiencies close to 6%.

Synthesis and biological activity of 5-(4-methoxyphenyl)-oxazole derivatives

5-(4′-Methoxyphenyl)-oxazole (MPO), originally reported as a synthetic compound, was isolated from fungal culture broth as an inhibitor of hatch and growth of Caenorhabditis elegans. Nineteen MPO derivatives were chemically synthesized, but showed no effect on C. elegans hatch and growth. These findings strongly suggested that the whole structure of MPO is essential for anti-C. elegans activity.

NOVEL NUCLEOSIDE PHOSPHORAMIDATE COMPOUND AND USE THEREOF

The present invention provides a novel nucleoside phosphoramidate compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection. The present invention also provides the pharmaceutical composition comprising a compound of the present invention, or a stereoisomer, salt, hydrate, solvate or crystal thereof and a use of the compound or the composition of the present invention in the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection. The compound of the present invention has a good anti-HCV effect.

POLYCYCLIC ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Programmed synthesis of arylthiazoles through sequential C-H couplings

A programmed synthesis of privileged arylthiazoles via sequential C-H couplings catalyzed by palladium or nickel catalysts has been accomplished. This versatile protocol can supply all possible arylthiazole substitution patterns (2-aryl, 4-aryl, 5-aryl, 2

Reigoselective arylation of thiazole derivatives at 5-position via Pd catalysis under ligand-free conditions

An efficient regioselective arylation of thiazole derivatives via Pd-catalyzed C-H activation is reported. The transformation was hypothesized through a Pd(0/II) catalytic cycle in the absence of special ligand sets. This method provided an efficient proc

Mild palladium-catalyzed regioselective direct arylation of azoles promoted by tetrabutylammonium acetate

A mild, general, and convenient palladium-catalyzed direct arylation of the 5-position of azoles with aryl bromides, efficiently promoted by tetrabutylammonium acetate, is described. 1-Methylpyrazole, oxazole, and thiazole reacted at 70°C in N,N-dimethyla

Synthesis of 5-arylthiazoles. Comparative study between Suzuki cross-coupling reaction and direct arylation

A facile synthetic route to the new thiazol-5-ylboronic acid pinacol ester was described herein. Its reactivity toward Suzuki cross-coupling reaction was studied to provide various 5-arylthiazoles. A comparative study between Suzuki cross-coupling reactio

Establishment of broadly applicable reaction conditions for the palladium-catalyzed direct arylation of heteroatom-containing aromatic compounds

Conditions for the palladium-catalyzed direct arylation of a wide range of heterocycles with aryl bromides are reported. Those conditions employ a stoichiometric ratio of both coupling partners, as well as a substoiehiometric quantity of pivalic acid, which results in significantly faster reactions. An evaluation of the influence of the nature of the aryl halide has also been carried out.