685534-98-9

Basic information

• Product Name: 2-Propenoic acid, 3-[2-(acetylamino)-4-chloro-5-methoxyphenyl]-, (2E)-
• CAS NO: 685534-98-9
• Molecular Formula: C12H12ClNO4
• Molecular Weight: 269.685
• Mol File: 685534-98-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-[2-(acetylamino)-4-chloro-5-methoxyphenyl]-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-[2-(acetylamino)-4-chloro-5-methoxyphenyl]-, (2E)-(685534-98-9)
• EPA Substance Registry System: 2-Propenoic acid, 3-[2-(acetylamino)-4-chloro-5-methoxyphenyl]-, (2E)-(685534-98-9)

Safety Data

• Hazardous Substances Data: 685534-98-9(Hazardous Substances Data)

Upstream product

• 685536-12-3 2-bromo-5-chloro-4-methoxy-phenylamine 
• 685535-00-6 (E)-3-(2-amino-4-chloro-5-methoxyphenyl)-acryclic acid ethyl ester 
• 868406-57-9 (E)-3-(2-amino-4-chloro-5-methoxyphenyl)-acrylic acid 
• 75-36-5 acetyl chloride 
• 5345-54-0 3-chloro-4-methoxyaniline 
• 7073-42-9 N-(3-chloro-4-methoxyphenyl)acetamide 
• 79-10-7 acrylic acid 

Downstream Products

• 685534-97-8 N-(5-chloro-2-[(E)-3-[(2R,5S)-4-(4-fluorobenzyl)-2,5-dimethylpiperazin-1-yl]-3-oxopropenyl]-4-methoxyphenyl)-acetamide 

Relevant articles and documents

Pd-catalyzed ortho-selective oxidative coupling of halogenated acetanilides with acrylates

Coupling of different halogenated acetanilides with acrylates using Pd-catalyzed ortho-selective C-H bond activation is reported. The yields of coupled products are low to high depending on the substrate. In general, arenes with electron-rich substituents like methoxy and methyl groups gave higher yields of the coupled products. The presence of the halogen substituent did not interfere with the activation process under these conditions.