68572-75-8

Upstream product

• 87-91-2 diethyl (2R,3R)-tartrate 
• 123-11-5 4-methoxy-benzaldehyde 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 

Downstream Products

• 158226-80-3 (2R,3R)-2-Hydroxy-3-(4-methoxy-benzyloxy)-succinic acid diethyl ester 
• 392250-80-5 (R)-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-(4-methoxy-benzyloxy)-acetaldehyde 
• 156696-22-9 (2S,3S)-3-[(4-methoxybenzyl)oxy]butane-1,2,4-triol 
• 158226-81-4 (2R,3R)-2-Methoxy-3-(4-methoxy-benzyloxy)-succinic acid diethyl ester 
• 1054786-44-5 (R)-3-Hydroxy-3-[(2R,4S,5S)-5-methoxy-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-2,2-dimethyl-propionic acid methyl ester 
• 158226-85-8 (2R,4R,5S)-5-Methoxy-2-(4-methoxy-phenyl)-[1,3]dioxane-4-carbaldehyde 
• 158226-83-6 [(2R,4S,5S)-5-Methoxy-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-methanol 
• 158226-82-5 (2S,3S)-2-Methoxy-3-(4-methoxy-benzyloxy)-butane-1,4-diol 
• 184839-79-0 C₃₃H₃₆O₆ 
• 184839-78-9 Methanesulfonic acid (1S,2S)-3-benzyloxy-1-benzyloxymethyl-2-(4-methoxy-benzyloxy)-propyl ester 

Relevant academic research and scientific papers

Stereoselective Total Synthesis of Pectinolides A, C, and H

A simple and straightforward stereoselective total synthesis of Pectinolides A, C, and H is described. The synthesis has been started from commercially available (+)-diethyl l-tartrate and involves Ohira-Bestmann reaction, Corey-Bakshi-Shibata (CBS) reduction, and Still-Gennari olefination as key steps.

Approaches to synthetic neolignans

Several synthetic approaches to neolignans with a C(8)-O-C(4′) linkage are described. Although direct introduction of a chiral aryloxy ether bond at the 8-position of protected phenylpropane derivatives was not successful, an efficient method for the synthesis of a chiral aryloxy ether bond has been developed, starting from a tartrate derivative.

Synthesis of the C13-C19 unit in the spiroketal fragment of calyculins

Synthesis of the C13-C19 unit 2 of calyculins (1) has been accomplished by use of the stereoselective aldol reaction of the aldehyde 10 from diethyl L-tartrate (3) with methyl trimethylsilyl dimethylketene acetal followed by the introduction of a cyano group as a C1-unit.