68578-79-0

Usage

Uses

Used in Organic Synthesis:
4,4'-(1,2-Diphenylethene-1,2-diyl)diphenol is used as a synthetic intermediate for the development of aggregation-induced emission (AIE) dyes. Its unique molecular structure allows for the formation of alkyl-halogen bonds, which can be further utilized in ether and polymer reactions via esterification. This makes TPE-DOH a valuable component in the synthesis of a wide range of organic compounds, including dyes, polymers, and other specialty chemicals.
Used in AIE Dye Synthesis:
In the field of AIE dye synthesis, 4,4'-(1,2-Diphenylethene-1,2-diyl)diphenol is used as a key intermediate for the production of novel dyes with unique photophysical properties. These AIE dyes exhibit enhanced fluorescence in the aggregated state, making them suitable for various applications, such as bioimaging, sensing, and optoelectronic devices.
Used in Pharmaceutical Industry:
4,4'-(1,2-Diphenylethene-1,2-diyl)diphenol can also be used in the pharmaceutical industry as a building block for the synthesis of drug candidates with potential therapeutic applications. Its unique structure and chemical properties can be exploited to design and develop new drugs with improved efficacy and selectivity.
Used in Material Science:
In the field of material science, 4,4'-(1,2-Diphenylethene-1,2-diyl)diphenol can be used as a precursor for the development of advanced materials with specific properties, such as self-healing materials, stimuli-responsive materials, and functional coatings. Its ability to form stable chemical bonds and its compatibility with various other chemical entities make it a promising candidate for the development of innovative materials with diverse applications.

Upstream product

• 119-61-9 benzophenone 
• 1137-42-4 4-Hydroxybenzophenone 
• 117-99-7 2-Hydroxybenzophenone 
• 68578-78-9 1,2-bis-(4-methoxyphenyl)-1,2-diphenylethene 
• 611-94-9 4-Methoxybenzophenone 
• 16513-74-9 <4-(Benzoyloxy)phenyl>phenylketon 
• 113736-78-0 4-Benzoyloxy-benzophenondichlorid 
• 113736-79-1 α,α'-Bis(4-benzoyloxyphenyl)-stilben 

Downstream Products

• 1237487-06-7 C₃₂H₂₄O₂ 
• 1220110-37-1 4,4'-(1,2-diphenylethenylene)diphenyl dipropiolate 
• 1263774-67-9 C₄₈H₅₂O₄ 
• 1263774-66-8 C₃₈H₃₂O₄ 
• 1542206-30-3 C₄₂H₅₂O₁₀ 
• 1542206-31-4 C₅₆H₆₄O₁₄S₂ 
• 1542206-32-5 C₆₄H₇₄N₂O₁₈ 
• 1542206-33-6 C₅₆H₅₈N₂O₁₈ 

Relevant academic research and scientific papers

Aggregation-Induced Emission Gemini Surfactant-Assisted Fabrication of Shape-Controlled Fluorescent Hollow Mesoporous Silica Nanoparticles

The development of particles that possess different properties has been a long-thought goal for producing multifunctional materials owing to their combination of performance. Herein, aggregation-induced emission (AIE) gemini surfactant-assisted preparatio

Fluorometric probing of the lipase level as acute pancreatitis biomarkers based on interfacially controlled aggregation-induced emission (AIE)

As a sudden inflammation of the pancreas, acute pancreatitis presents severe complications and a high mortality rate, despite treatment. Lipase in serum serves as an essential biomarker of acute pancreatitis and even pancreatic cancer. Therefore, developing robust, convenient and sensitive probing of lipase levels is greatly needed. In this work, we present glutamate functionalized tetraphenylethylene (TPE) as a "turn-on" fluorescent probe (S1) based on the aggregation-induced emission (AIE) mechanism for lipase levels with new recognition units. In heterogeneous media, the hydrophilic amino and carboxyl groups in the probe were specifically introduced to facilitate its full access to lipase at the oil-water interface and achieve an interfacially controlled AIE process. The linear response of fluorescence ranging from 0 to 80 U L-1, which included the concentration range of the lipase level in human serum, considering the dilution factor if necessary, the limit of detection as low as 0.13 U L-1, and the fast response time (7 min) were determined. The value of the apparent Michaelis-Menten constant (Km) was obtained as 4.23 μM, which indicated superior affinity between lipase and the probe molecule. The selectivity, photostability, dynamic monitoring of the enzymatic reaction, and preliminary commercial enzyme activity screening were summarized. As far as we know, this is the fastest, easiest and most sensitive method for lipase level probing in the reported literature. Finally, probing the lipase level for the first time in real human serum samples was also conducted successfully.

Synthesis and Design of Aggregation-Induced Emission Surfactants: Direct Observation of Micelle Transitions and Microemulsion Droplets

The direct visualization of micelle transitions is a long-standing challenge owing to the intractable aggregation-caused quenching of light emission in the micelle solution. Herein, we report the synthesis of a surfactant with a tetraphenylethene (TPE) co

Supermolecular self assembly of AIE-active nanoprobes: Fabrication and bioimaging applications

Luminescent polymeric nanoparticles (LPNs) have attracted great attention in the field of biosensors, bioimaging and therapy. In this work, we reported that novel aggregation induced emission dye based LPNs can be facilely and efficiently fabricated throu

Fluorescent PEGulated Oligourethane Nanoparticles for Long-Term Cellular Tracing

We have introduced a new ABA-type amphiphilic block copolymer consisting of functional oligourethane hydrophobic blocks and two polyethylene glycol (PEG) hydrophilic blocks. The polymer was synthesized in a single step by step-growth polymerization betwee

Luminescent two-way reversible shape memory polymers prepared by hydroxyl-yne click polymerization

Two-way reversible shape memory polymers (2W-SMPs), capable of changing their shape reversibly, are highly desirable for many potential applications. However, the polymerization reactions used for preparing 2W-SMPs always require harsh conditions, such as

Fibrous testing papers for fluorescence trace sensing and photodynamic destruction of antibiotic-resistant bacteria

The increasing prevalence of antibiotic-resistant bacteria needs rapid identification and efficient destruction routes. This study proposes testing paper derived from electrospun fibrous mats and aggregation-induced emission (AIE) probes for trace sensing

Supramolecular Assembly-Induced Emission Enhancement for Efficient Mercury(II) Detection and Removal

New strategies that can simultaneously detect and remove highly toxic environmental pollutants such as heavy metal ions are still in urgent need. Herein, through supramolecular host-guest interactions, a fluorescent supramolecular polymer has been facilel

Synthesis, characterization and visible light activated fluorescence of azo caged aggregation-induced emission polymers

Tetraphenylethylene (TPE) based aggregation-induced emission (AIE) polymers containing different degrees of functionalization of photobleachable azo chromophores were developed and their photophysical properties were explored. The synthesized epoxy monome

H2O2-Responsive amphiphilic polymer with aggregation-induced emission (AIE) for DOX delivery and tumor therapy

Stimuli-responsive drug delivery systems (DDSs) based on amphiphilic polymers have attracted much attention. In this study, we reported an innovative H2O2-responsive amphiphilic polymer (TBP), bearing a H2O2-sen