686266-22-8

Basic information

• Product Name: N-[2-(aminosulfonyl)phenyl]-1-(benzyloxy)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide
• Synonyms: N-[2-(aminosulfonyl)phenyl]-1-(benzyloxy)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide
• CAS NO: 686266-22-8
• Molecular Weight: 466.474
• Mol File: 686266-22-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-[2-(aminosulfonyl)phenyl]-1-(benzyloxy)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(aminosulfonyl)phenyl]-1-(benzyloxy)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide(686266-22-8)
• EPA Substance Registry System: N-[2-(aminosulfonyl)phenyl]-1-(benzyloxy)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide(686266-22-8)

Safety Data

• Hazardous Substances Data: 686266-22-8(Hazardous Substances Data)

Upstream product

• 54734-84-8 2-amino-5-bromobenzenesulfonamide 
• 179064-00-7 1-benzyl-4-hydroxy-2-oxo-1,2-dihydro[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 686266-21-7 ethyl 1-(benzyloxy)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate 
• 686266-20-6 ethyl 2-[(benzyloxy)(3-ethoxy-3-oxopropanoyl)amino]nicotinate 
• 3306-62-5 2-AMINOBENZENESULFONAMIDE 

Downstream Products

• 686262-92-0 1-butyl-3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1,8-naphthyridin-2(1H)-one 

Relevant articles and documents

Inhibitors of HCV NS5B polymerase: Synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines

N-1-Alkylamino and N-1-alkyloxy-4-hydroxyquinolon-3-yl benzothiadiazines were synthesized and evaluated as inhibitors of genotype 1 HCV polymerase. The N-1-alkyloxy derivatives were not potent inhibitors, however N-1-alkylamino derivatives displayed compa

Anti-infective agents

Compounds having the formula are hepatitis C (HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.