686343-78-2

Basic information

• Product Name: methyl (S)-3-(dibenzylamino)-4-phenylbutanoate
• Synonyms: methyl (S)-3-(dibenzylamino)-4-phenylbutanoate
• CAS NO: 686343-78-2
• Molecular Weight: 373.495
• Mol File: 686343-78-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl (S)-3-(dibenzylamino)-4-phenylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (S)-3-(dibenzylamino)-4-phenylbutanoate(686343-78-2)
• EPA Substance Registry System: methyl (S)-3-(dibenzylamino)-4-phenylbutanoate(686343-78-2)

Safety Data

• Hazardous Substances Data: 686343-78-2(Hazardous Substances Data)

Upstream product

• 123054-12-6 (2S)-N,N-dibenzylphenylalaninal 
• 100-39-0 benzyl bromide 
• 68978-89-2 homo-β-phenylalanine methyl ester 
• 184774-09-2 N,N-dibenzyl-L-phenylalanine methyl ester 
• 74-95-3 1,1-dibromomethane 

Downstream Products

• 861432-37-3 methyl (2S,3S)-3-(dibenzylamino)-2-[N',N''-(di-tert-butoxycarbonyl)-hydrazino]-3-phenylbutanoate 

Relevant articles and documents

Efficient synthesis of orthogonally protected anti-2,3-diamino acids

An asymmetric synthesis of anti-2,3-diamino acids is reported. The enolates of N,N-dibenzylated β3-amino esters were treated with di-tert-butyl azodicarboxylate (DBAD) to afford their N′,N″-di-Boc- 2-hydrazino derivatives with excellent anti di

Kowalski ester homologation. Application to the synthesis of β-amino esters

The Kowalski ester homologation protocol has been applied to a representative range of α-amino esters to provide β-amino esters with excellent levels of enantio- and diastereocontrol. A key feature of this chemistry is the nature of the N-protecting group that is employed.