686709-51-3

Usage

Uses

Used in Pharmaceutical Research:
1-(4-AMINOPHENYL)-N,N-DIMETHYL-3-PYRROLIDINAMINE is used as a building block for the synthesis of various pharmaceutical drugs. Its unique structure allows for the creation of biologically active molecules that can be utilized in the development of new medications.
Used in Agrochemicals:
In the agrochemical industry, 1-(4-AMINOPHENYL)-N,N-DIMETHYL-3-PYRROLIDINAMINE is used as a key component in the synthesis of various agrochemicals. Its incorporation into these products can enhance their effectiveness and contribute to improved agricultural practices.
Used in Organic Synthesis:
1-(4-AMINOPHENYL)-N,N-DIMETHYL-3-PYRROLIDINAMINE is employed as an essential compound in organic synthesis. Its versatile structure enables the creation of a wide range of chemical products, making it a valuable asset in this field.
Used in Photoredox Catalysis:
1-(4-AMINOPHENYL)-N,N-DIMETHYL-3-PYRROLIDINAMINE has been studied for its potential use in photoredox catalysis, a process that involves the transfer of electrons during the absorption and release of light energy. Its application in this area could lead to advancements in various chemical reactions and processes.

Upstream product

• 69478-75-7 dimethyl-pyrrolidin-3-yl-amine 
• 350-46-9 4-Fluoronitrobenzene 
• 361346-46-5 [1-(4-nitrophenyl)-pyrrolidin-3-yl] dimethylamine 

Downstream Products

• 748183-91-7 6-chloro-N-[4-(3-dimethylamino-pyrrolidin-1-yl)-phenyl]-nicotinamide 
• 748183-84-8 N-[4-(3-dimethylaminopyrrolidin-1-yl)phenyl]-6-hydroxynicotinamide 
• 748183-37-1 piperidine-4-carboxylic acid [4-(3-dimethylamino-pyrrolidin-1-yl)-phenyl]-amide 
• 748183-96-2 4-[4-(3-dimethylaminopyrrolidin-1-yl)phenylcarbamoyl]phenyl acetate 
• 748169-29-1 2',4'-Difluorobiphenyl-4-carboxylic Acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide 
• 748169-32-6 N-[4-(3-Dimethylaminopyrrolidin-1-yl)phenyl]-3-fluoro-4-(4-methylpiperidin-1-yl)-benzamide 
• 748183-95-1 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide 
• 748183-44-0 N-[4-(3-Dimethylaminopyrrolidin-1-yl)phenyl]terephthalamic acid methyl ester 
• 748183-78-0 5-bromofuran-2-carboxylic acid [4-[3-(dimethylamino)-pyrrolidin-1-yl]-phenyl]-amide 
• 748183-90-6 5-Chloropyridine-2-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide 

Relevant academic research and scientific papers

COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS

The present application provides novel optionally substituted fused pyridine and pyrimidine bicyclic compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful in co-regulating FAK and/or Src activity by administering a therapeutically effective amount of one or more of the compounds to a subject. By doing so, these compounds are effective in treating conditions associated with the dysregulation of the FAK and/or Src pathway. Advantageously, these compounds perform as dual FAK and/or Src inhibitors. A variety of conditions can be treated using these compounds and include diseases which are characterized by inflammation or abnormal cellular proliferation. In one embodiment, the disease is cancer.

IMIDAZOPYRIDINES AS A NOVEL SCAFFOLD FOR MULTI-TARGETED KINASE INHIBITION

Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed. Formula (I).

INDOLINONE DERIVATIVES AND THEIR USE IN TREATING DISEASE-STATES SUCH AS CANCER

The present invention encompasses compounds of general formula (1) wherein R1 to R4 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use for preparing a pharmaceutical composition having the above-mentioned properties.

1-(4-Amino-phenyl)-pyrrolidin-3-yl-amine and 6-(3-amino-pyrrolidin-1-yl)- pyridin-3-yl-amine derivatives as melanin-concentrating hormone receptor-1 antagonists

Derivatives of 1-(4-amino-phenyl)-pyrrolidin-3-yl-amine and 6-(3-amino-pyrrolidin-1-yl)-pyridin-3-yl-amine were identified as potent and functionally active MCH-R1 antagonists. One compound with Ki = 2.3 nM demonstrated good oral bioavailabilit

Substituted N-aryl heterocycles, process for their preparation and their use as medicaments

The invention relates to substituted N-aryl heterocycles and to the physiologically tolerated salts and physiologically functional derivatives thereof. Compounds of the formula I in which the radicals have the stated meanings, the N-oxides and the physiologically tolerated salts thereof and process for the preparation thereof are described. The compounds are suitable for example as anorectic agents.