6869-07-4

Basic information

• Product Name: A,A'-HYDRAZODIISOBUTYRONITRILE
• Synonyms: 2,2'-HYDRAZO-BIS(2-METHYLPROPIONITRILE);A,A'-HYDRAZODIISOBUTYRONITRILE;2,2'-(Hydrazine-1,2-diyl)bis(2-methylpropanenitrile);2,2'-Hydrazobis(2-methylpropiononitrile);2,2'-Hydrazobis(isobutyronitrile);2-[2-(1-Cyano-1-methyl-ethyl)hydrazino]-2-methyl-propanenitrile;2,2-HYDRAZOBIS[2-METHYLPROPANENITRILE]
• CAS NO: 6869-07-4
• Molecular Formula: C₈H₁₄N₄
• Molecular Weight: 166.22
• Mol File: 6869-07-4.mol

Chemical Properties

• Boiling Point: 284.45°C (rough estimate)
• Appearance: /
• Density: 1.0186 (rough estimate)
• Refractive Index: 1.4910 (estimate)
• CAS DataBase Reference: A,A'-HYDRAZODIISOBUTYRONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: A,A'-HYDRAZODIISOBUTYRONITRILE(6869-07-4)
• EPA Substance Registry System: A,A'-HYDRAZODIISOBUTYRONITRILE(6869-07-4)

Safety Data

• Hazardous Substances Data: 6869-07-4(Hazardous Substances Data)

Upstream product

• 143-33-9 sodium cyanide 
• 67-64-1 acetone 
• 74-90-8 hydrogen cyanide 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 151-50-8 potassium cyanide 
• 7732-18-5 water 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 78-82-0 Isobutyronitrile 
• 78-67-1 2,2'-azobis(isobutyronitrile) 
• 74-90-8 hydrogen cyanide 
• 67-64-1 acetone 
• 3879-07-0 diethyl 2,2'-azobis(2-methylpropionate) 
• 2589-57-3 dimethyl 2,2'-azobis(isobutyrate) 
• 3333-52-6 2,2,3,3-tetramethylsuccinonitrile 
• 93214-34-7 α-(4-Cyanoisopropyl-2,6-di-tert-butyl-1-oxo-2,5-cyclohexadienyl)-N-tert-butylnitron 
• 93214-45-0 1,3,5-Tri-tert-butyl-3-(2-cyanoprop-2-yl)-6-oxo-cyclohexadi-1,4-dien 

Relevant articles and documents

Azobisisobutyronitrile preparation method

The present invention relates to an azobisisobutyronitrile preparation method, which comprises: carrying out a reaction on sodium hypochlorite, ammonia and acetone to prepare an acetone azine synthesis solution; purifying to obtain acetone azine with a mass content of not less than 90%; reacting with hydrogen cyanide to obtain hydrogenated azobisisobutyronitrile; and oxidizing with chlorine gas orhydrogen peroxide to obtain an azobisisobutyronitrile solution. Compared to the conventional process, the method of the present invention can simplify the production process, shorten the production cycle, and reduce the consumption of steam and circulating water so as to increase the yield of azobisisobutyronitrile and reduce the production cost.

Metal bridging for directing and accelerating electron transfer as exemplified by harnessing the reactivity of AIBN

A new strategy for tuning the electron transfer between radicals and enolates has been developed. This method elicits the innate reactivity of AIBN with a copper catalyst and enables a cascade reaction with cinnamic acids. Electron paramagnetic resonance studies and control experiments indicate that the redox-active copper species not only activates the radical by coordination, but also serves as a bridge to bring the radical and nucleophile within close proximity to facilitate electron transfer. By exploiting possible combinations of redox-active metals and radical entities with suitable coordinating functional groups, this strategy should contribute to the development of a broad range of radical-based reactions.

Asymmetric nitrogen 78. Sterically hindered inversion of nitrogen atoms in cyclic hydrazines: N,N'-dialkyl-1,3,4-oxadiazolidines; 1,3,4-thiadiazolidine; and 4,5-benzo-1,2,3,6-tetrahydropyridazine

N,N'-Diisopropyl-substituted 1,3,4-oxadiazolidine 3c, 1,3,4-thiadiazolidine 6, 4,5-benzo-1,2,3,6-tetrahydropyridazine 8, and new 3,4-dialkyl-1,3,4-oxadiazolines 9-14 were synthesized and studied.The configurational stability of the N atoms does not change on going from compounds 3c to its S-analog 6 and decreases in the case of pyridazine 8. 3,4-Di-tert-alkyl-1,3,4-oxadiazolidines 3d and 11-14 were found to be promising objects for optical resolution. - Keywords: N,N'-dialkyl-substituted 1,3,4-oxadiazolidines; 1,3,4-thiadiazolidine; 4,5-benzo-1,2,3,6-tetrahydropyridazine; nitrogen inversion; 1H, 13C NMR.

A FAST N-SUBSTITUTED α-AMINONITRILE SYNTHESIS

A series of α-aminonitriles bearing various functionalities was prepared by reacting a neat mixture of an aldehyde or ketone, an amine and trimethylsilyl cyanide.The reaction was essentially complete in 5 minutes.