68692-70-6

Upstream product

• 130818-20-1 2-(2-(4-methoxyphenyl)ethynyl)benzoic acid methyl ester 
• 48121-13-7 copper(I) 4-methoxyphenylacetylenide 
• 60494-73-7 (2-methoxycarbonylbenzyl)triphenylphosphonium bromide 
• 123-11-5 4-methoxy-benzaldehyde 
• 768-60-5 4-methoxyphenylacetylen 

Downstream Products

• 66374-13-8 cis-4'-methoxystilbene-2-carboxylic acid 
• 66374-13-8 2-[2-(4-methoxyphenyl)ethenyl]benzoic acid 

Relevant academic research and scientific papers

CO-Free Enantioselective Hydroformylation of Functionalised Alkenes: Using a Dual Catalyst System to Give Improved Selectivity and Yield

The scope of carbon monoxide-free Asymmetric Transfer HydroFormylation (ATHF) procedures using a highly active single catalyst system derived from 1,2-bis-((2,5)-diphenylphospholano)ethane as chiral ligand has been studied. This reveals some highly successful reactions, but also significant limitations. The development of a new protocol in which a catalyst for formaldehyde decomposition to CO and H2 is combined with the catalyst of choice for the subsequent asymmetric hydroformylation is described. This enables ATHF reactions that were problematic to be significantly improved. The new method has been used in the synthesis of several key precursors to biologically active molecules. (Figure presented.).

DIBENZOCYCLOHEPTENE COMPOUND

The present invention discloses a dibenzocycloheptene compound represented by the formula (I): ???wherein R1: hydrogen atom, halogen atom, etc., R2: hydrogen atom, halogen atom, etc., A: 5-membered or 6-membered heteroaromatic ring group containing 1 to 3 hetero atom(s) selected from the group consisting of nitrogen atom, oxygen atom and sulfur atom, and the heteroaromatic ring group, etc. may have halogen atom, nitrogen atom, etc. as substituent(s), B: formula; -CH=CH-, formula; -CH2O-, etc., Y: C1-C10 alkylene group which may have halogen atom, etc. as substituent(s), etc., Z: carboxyl group which may be protected, etc., m: an integer of 1 to 4, n: an integer of 1 to 3, ???------ represents a single bond or a double bond, or a pharmaceutically acceptable salt thereof and a medical composition containing the same as an effective ingredient which has leukotriene C4 antagonistic action and leukotriene E4 antagonistic action in addition to potent leukotriene D4 antagonistic action, and useful as antiasthmatic agent, antiallergic agent and anti-inflammatory agent.

Transmission of Polar Effects. Part 21. Alkaline Hydrolysis of the 2'- and 4'-substituted 2-Methoxycarbonyldiphenylacetylenes and (Z)-2'- and -4'- Substituted 2-Methoxycarbonylstilbenes and the Ionisation and Esterification, with Diazodiphenylmethane of t

The rate coefficients for the alkaline hydrolysis of a series of 2'- and 4'-substituted 2-methoxycarbonyldiphenylacetylenes and (Z)-2-methoxycarbonylstilbenes have been determined in 70percent (v/v) dimethyl sulphoxide-water at both 30.0 and 50.0 deg C an