68726-79-4

Upstream product

• 61260-15-9 dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate 
• 497-23-4 2-buten-4-olide 

Downstream Products

• 125494-99-7 9-Benzyloxy-4-methoxy-3H-naphtho[2,3-c]furan-1-one 
• 308277-85-2 (9-benzyloxy-4-methoxy-1,3-dihydro-naphtho[2,3-c]furan-1-yl)-acetic acid 
• 1026372-60-0 (9-benzyloxy-1-hydroxy-4-methoxy-1,3-dihydro-naphtho[2,3-c]furan-1-yl)-acetic acid tert-butyl ester 

Relevant academic research and scientific papers

An annulation reaction to naphthalene-1,4-diols using dimethyl phthalide-3-phosphonates

A regioselective annulation to naphthalene ring systems from dimethyl phthalide-3-phosphonates and electron-deficient olefins is described.

Synthesis of the functionalized tricyclic core of lactonamycin by oxidative dearomatization.

[reaction: see text] We report in this Letter a synthesis of the densely oxygenated CDEF ring system (27) corresponding to that found in the recently discovered antibiotic lactonamycin. The key steps in the synthesis consist of an intramolecular Wessely oxidative lactonization of acid 18, followed by a hydroxyl-directed epoxidation of enol ether 21.